Hostname: page-component-848d4c4894-89wxm Total loading time: 0 Render date: 2024-07-08T03:04:13.993Z Has data issue: false hasContentIssue false

Rate of Latent Tuberculosis Infection Detected by Occupational Health Screening of Nurses New to a London Teaching Hospital

Published online by Cambridge University Press:  02 January 2015

Priya Khanna
Affiliation:
Department of Microbiology, London, United Kingdom
Vladyslav Nikolayevskyy
Affiliation:
Queen Mary's School of Medicine and Dentistry, London, United Kingdom Barts and the London National Health Service Trust, and the Mycobacterium Reference Unit, Health Promotion Agency, London, United Kingdom
Fiona Warburton
Affiliation:
Joint R&D Office, London, United Kingdom
Elek Dobson
Affiliation:
Occupational Health Service, London, United Kingdom
Francis Drobniewski*
Affiliation:
Queen Mary's School of Medicine and Dentistry, London, United Kingdom Barts and the London National Health Service Trust, and the Mycobacterium Reference Unit, Health Promotion Agency, London, United Kingdom
*
National Mycobacterium Reference Unit, Queen Mary's School of Medicine and Dentistry, 2 Newark St., London, El 2AT, United Kingdom(f.drobniewski@qmul.ac.uk)

Abstract

The prevalence of latent tuberculosis infection in a cohort of nurses new to a London hospital was 7.6% (13 of 171), using an interferon-γ(IFN-γ) release assay, and 16.2% (24 of 148), using the tuberculin skin test. On multivariate analysis, birth in a country with tuberculosis prevalence of more than 40 cases per 100,000 population was associated with positive results of both the IFN-γ release assay and the tuberculin skin test.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Donaldson, L. Introduction from the chief medical officer (CMO). In: Tuberculosis Update. March 2008. Available at: http://www.hpa.org.uk/web/HPAwebFile/HPAweb_C/1207035533566. Accessed August 10,2008.Google Scholar
2.Clinical guideline N33. Tuberculosis: clinical diagnosis and management of tuberculosis, and measures for its prevention and control. National Institute for Health and Clinical Excellence; 2006. Available at: http://www.nice.org.uk/guidance/CG33/niceguidance/pdf/English. Accessed May 1, 2009.Google Scholar
3.Anderson, C, Abubakar, I, Maguire, H, Sonnenberg, P. Survey of tuberculosis incidents in hospital healthcare workers, England and Wales, 2005. J Pub Health (Oxf) 2007;29:292297.CrossRefGoogle ScholarPubMed
4.Tuberculosis: BCG vaccination immunisation against infectious disease. In: Immunisation against Infectious Diseases-”The Green Book.” London, United Kingdom: The Stationery Office, under licence from the Department of Health; 2006:391408. Available at: http://www.dh.gov.uk/en/publichealth/healthprotection/immunisation/greenbook. Accessed April 27, 2009.Google Scholar
5.World Health Organization (WHO). Global tuberculosis control: surveillance, planning, financing. In: WHO Report. Geneva, Switzerland; 2007. Available at: http://www.who.int/tb/publications/global_report/en/. Accessed June 19, 2007.Google Scholar
6.Mycobacterium tuberculosis transmission in a newborn nursery and maternity ward-New York City, 2003. MMWR Morb Mortal Wkly Rep 2005;54:12801283.Google Scholar
7.Aiken, LH, Buchan, J, Sochalski, J, Nichols, B, Powell, M. Trends in international nurse migration. Health Affairs 2004;23:6977.Google Scholar
8.Mazurek, GH, Jereb, I, Lobue, P, Iademarco, MF, Metchock, B, Vernon, A. Guidelines for using the QuantiFERON-TB Gold test for detecting Mycobacterium tuberculosis infection, United States. MMWR Recomm Rep 2005;54(RR-15):4955.Google Scholar
9.Drobniewski, F, Balabanova, Y, Zakamova, E, Nikolayevskyy, V, Fedorin, I. Rates of latent tuberculosis in health care staff in Russia. PLoS Med 2007;4:e55.Google Scholar
10.Harada, N, Nakajima, Y, Higuchi, K, Sekiya, Y, Rothel, I, Mori, T. Screening for tuberculosis infection using whole-blood interferon-gamma and Mantoux testing among Japanese healthcare workers. Infect Control Hosp Epidemiol 2006;27:442448.Google Scholar