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Pediatric Severe Sepsis/Septic Shock Associated with Healthcare-Associated Infections

  • Sarah B. Klieger (a1), Julie C. Fitzgerald (a2) (a3), Scott L. Weiss (a2) (a3), Fran Balamuth (a3) (a4), Eva Teszner (a5), Julia S. Sammons (a1) (a3) (a5) and Susan E. Coffin (a1) (a3) (a5)...

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Corresponding author

Address correspondence to: Sarah B. Klieger, Division of Infectious Diseases, The Children’s Hospital of Philadelphia, 3535 Market Street, Suite 1519, Philadelphia, PA, 19104 (klieger@email.chop.edu).

References

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1. Magill, SS, Edwards, JR, Bamberg, W, et al. Multistate point-prevalence survey of health care-associated infections. N Engl J Med 2014;370:11981208.
2. Carey, AJ, Saiman, L, Polin, RA. Hospital-acquired infections in the NICU: epidemiology for the new millennium. Clin Perinatol 2008;35:223249.
3. Weiss, SL, Fitzgerald, JC, Pappachan, J, et al. Global epidemiology of pediatric severe sepsis: The Sepsis Prevalence, Outcomes and Therapies Study. Am J Resp Crit Care 2015;191:11471157.
4. Levy, MM, Artigas, A, Phillips, GS, et al. Outcomes of the Surviving Sepsis Campaign in intensive care units in the USA and Europe: a prospective cohort study. Lancet Infect Dis 2012;12:919924.
5. Odetola, FO, Gebremariam, A, Freed, GL. Patient and hospital correlates of clinical outcomes and resource utilization in severe pediatric sepsis. Pediatrics 2007;119:487494.
6. Hartman, ME, Linde-Zwirble, WT, Angus, DC, Watson, RS. Trends in the epidemiology of pediatric severe sepsis. Pediatr Crit Care Med 2013;14:686693.
7. Surveillance definitions for specific types of infections. Centers for Disease Control and Prevention website. http://www.cdc.gov/nhsn/PDFs/pscManual/17pscNosInfDef_current.pdf. Published 2015. Accessed August 25, 2015.
8. Goldstein, B, Giroir, B, Randolph, A. International pediatric sepsis consensus conference: definitions for sepsis and organ dysfunction in pediatrics. Pediatr Crit Care Med 2005;6:28.
9. Feudtner, C, Christakis, DA, Connell, FA. Pediatric deaths attributable to complex chronic conditions: a population-based study of Washington State, 1980–1997. Pediatrics 2000;106:205209.
10. Silber, JH, Williams, SV, Krakauer, H, Schwartz, JS. Hospital and patient characteristics associated with death after surgery: a study of adverse occurrence and failure to rescue. Med Care 1992;30:615629.

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