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Nosocomial Outbreak of Clostridium difficile-Associated Disease in a Pediatric Intensive Care Unit in Madrid

Published online by Cambridge University Press:  02 January 2015

Amaya Bustinza*
Affiliation:
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Maria José Solana
Affiliation:
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Belén Padilla
Affiliation:
Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Jesús López-Herce
Affiliation:
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Maria José Santiago
Affiliation:
Pediatric Intensive Care Unit, Hospital General Universitario Gregorio Marañón, Madrid, Spain
Mercedes Marin
Affiliation:
Department of Microbiology and Infectious Diseases, Hospital General Universitario Gregorio Marañón, Madrid, Spain
*
Hospital General Universitario Gregorio Marañón, Dr. Castelo 47, 28009-Madrid, Spain (abustinza.hgugm@salud.madrid.org)

Abstract

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Type
Research Briefs
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2009

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References

1.Vora, S, Glikman, D, Kahanna, M, Daum, RS. Severe diarrhea and shock. Pediatr Infect Dis J 2006;25:279285.CrossRefGoogle ScholarPubMed
2.Kuijper, EJ, Coignard, B, Tüll, P. Emergence of Clostridium difftcile-as-sociated disease in North America and Europe. Clin Microbiol Infect 2006;12(Suppl 6):218.Google Scholar
3.Marra, AR, Edmond, MB, Wenzel, RP, Bearman, GM. Hospital-acquired Clostridium difficile-associated disease in the intensive care unit setting: epidemiology, clinical course, and outcome. BMC Infect Dis 2007;7:42.CrossRefGoogle ScholarPubMed
4.Bouza, E, Peláez, T, Alonso, R, Catalan, P, Muñoz, P, Creixems, MR. “Second-look” cytotoxicity: an evaluation of culture plus cytotoxin assay of Clostridium difficile isolates in the laboratory diagnosis of CDAD. J Hosp Infect 2001;48:233237.CrossRefGoogle ScholarPubMed
5.Stubbs, S LJ, Brazier, JS, O'Neill, GL, Duerden, BI. PCR targeted to the 16S-23S rRNA gene intergenic spacer region of Clostridium difficile and construction of a library consisting of 116 different PCR ribotypes. J Clin Microbiol 1999;37:461463.Google Scholar
6.Ferroni, A, Merckx, J, Ancelle, T, et al.Nosocomial outbreak of Clostridium difficile diarrhea in a pediatric service. Eur J Clin Microbiol Infect Dis 1997;16:928933.Google Scholar
7.Gould, CV, McDonald, LC. Clostridium difficile colitis. Critical Care 2008;12:203.CrossRefGoogle ScholarPubMed
8.Cookson, B. Hypervirulent strains of Clostridium difficile. Postgrad Med J 2007;83:291295.CrossRefGoogle ScholarPubMed
9.Miller, MA. Clinical management of Clostridium difficile-associated disease. Clin Infect Dis 2007;45:S122S128.Google Scholar
10.Nelson, R. Antibiotic treatment for Clostridium difficile-associated diarrhea in adults. Cochrane Database Syst Rev 2007;(3):CD004610.Google Scholar