Hostname: page-component-7c8c6479df-hgkh8 Total loading time: 0 Render date: 2024-03-18T14:29:49.930Z Has data issue: false hasContentIssue false

Impact of Different Catheter Lock Strategies on Bacterial Colonization of Permanent Central Venous Hemodialysis Catheters

Published online by Cambridge University Press:  02 January 2015

Stefan Erb*
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Switzerland
Andreas F. Widmer
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Switzerland
Sarah Tschudin-Sutter
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Switzerland
Ursula Neff
Affiliation:
Division of Infectious Diseases and Hospital Epidemiology, University Hospital of Basel, Switzerland
Manuela Fischer
Affiliation:
Division of Nephrology and Transplantation Immunology, University Hospital of Basel, Switzerland
Michael Dickenmann
Affiliation:
Division of Nephrology and Transplantation Immunology, University Hospital of Basel, Switzerland
Philipp Grosse
Affiliation:
Division of Nephrology and Transplantation Immunology, University Hospital of Basel, Switzerland
*
Division of Infectious Diseases and Hospital Epidemiology, University Hospital Basel, Petersgraben 4, 4031 Basel, Switzerland (andreas.widmer@usb.ch)

Abstract

Thirty-nine hemodialysis patients with permanent central venous catheters were analyzed for bacterial catheter colonization comparing different catheter-lock strategies. The closed needleless Tego connector with sodium chloride lock solution was significantly more frequently colonized with bacteria than the standard catheter caps with antimicrobially active citrate lock solution (odds ratio, 0.22 [95% confidence interval, 0.07–0.71]; P = .011).

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2013

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1.Allon, M, Daugirdas, J, Depner, TA, Greene, T, Ornt, D, Schwab, SJ. Effect of change in vascular access on patient mortality in hemodialysis patients. Am J Kidney Dis 2006;47(3):469477.Google Scholar
2.O'Grady, NP, Alexander, M, Burns, LA, et al. Guidelines for the prevention of intravascular catheter-related infections. Am J Infect Control 2011;39(suppl 1):S1S34.Google Scholar
3.Salgado, CD, Chinnes, L, Paczesny, TH, Cantey, JR. Increased rate of catheter-related bloodstream infection associated with use of a needleless mechanical valve device at a long-term acute care hospital. Infect Control Hosp Epidemiol 2007;28(6):684688.Google Scholar
4.ICU Medical. The Benefits of a Saline Flushing Protocol when using the Tego® Needlefree Hemodialysis Connector. San Clemente, CA: ICU Medical, 2012. http://www.icumed.com/media/95894/M1-1302_Saline_Flush_Recommendation_Tego.pdf.Google Scholar
5.McAfee, N, Seidel, K, Watkins, S, Flynn, JT. A continuous quality improvement project to decrease hemodialysis catheter infections in pediatric patients: use of a closed luer-lock access cap. Nephrol Nurs J 2010;37(5):541545.Google Scholar
6.Yahav, D, Rozen-Zvi, B, Gafter-Gvili, A, Leibovici, L, Gafter, U, Paul, M. Antimicrobial lock solutions for the prevention of infections associated with intravascular catheters in patients undergoing hemodialysis: systematic review and meta-analysis of randomized, controlled trials. Clin Infect Dis 2008;47(l):8393.Google Scholar
7.Weijmer, MC, van den Dorpel, MA, Van de Ven, PJ, et al. Randomized, clinical trial comparison of trisodium citrate 30% and heparin as catheter-locking solution in hemodialysis patients. JAm Soc Nephrol 2005;16(9):27692777.Google Scholar
8.Haley, RW, Morgan, WM, Culver, DH, et al. Update from the SENIC project. Hospital infection control: recent progress and opportunities under prospective payment. Am J Infect Control 1985;13(3):97108.CrossRefGoogle ScholarPubMed
9.Patel, PR, Yi, SH, Booth, S, et al. Bloodstream infection rates in outpatient hemodialysis facilities participating in a collaborative prevention effort: a quality improvement report. Am J Kidney Dis 2013;62(2):322330.Google Scholar
10.Rodriguez-Aranda, A, Alcazar, JM, Sanz, F, et al. Endoluminal colonization as a risk factor for coagulase-negative staphylococcal catheter-related bloodstream infections in haemodialysis patients. Nephrol Dial Transplant 2011;26(3):948955.Google Scholar