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Efficacy of a stewardship intervention focused on reducing unnecessary use of non–Clostridioides difficile antibiotics in patients with Clostridioides difficile infection

  • Michelle T. Hecker (a1) (a2), Andrea H. Son (a3), Heba Alhmidi (a4), Brigid M. Wilson (a5), Peter M. Wiest (a1) (a2) and Curtis J. Donskey (a2) (a5)...

Abstract

In a tertiary-care hospital and affiliated long-term care facility, a stewardship intervention focused on patients with Clostridioides difficile infection (CDI) was associated with a significant reduction in unnecessary non-CDI antibiotic therapy. However, there was no significant reduction in total non-CDI therapy or in the frequency of CDI recurrence.

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Corresponding author

Author for correspondence: Curtis J. Donskey, Email: Curtis.Donskey@va.gov

References

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6.Jury, LA, Tomas, M, Kundrapu, S, Sitzlar, B, Donskey, CJ.A Clostridium difficile infection (CDI) stewardship initiative improves adherence to practice guidelines for management of CDI. Infect Control Hosp Epidemiol 2013;34:12221224.10.1086/673459
7.Hecker, MT, Ho, E, Donskey, CJ.Fear of failure: engaging patients in antimicrobial stewardship after fecal transplantation for recurrent Clostridium difficile infection. Infect Control Hosp Epidemiol 2017;38:127129.10.1017/ice.2016.236
8.Cohen, SH, Gerding, DN, Johnson, S, et al.Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol 2010;31:431455.10.1086/651706
9.Hecker, MT, Aron, DC, Patel, NP, Lehmann, MK, Donskey, CJ.Unnecessary use of antimicrobials in hospitalized patients. Arch Intern Med 2003;163:972978.10.1001/archinte.163.8.972
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Efficacy of a stewardship intervention focused on reducing unnecessary use of non–Clostridioides difficile antibiotics in patients with Clostridioides difficile infection

  • Michelle T. Hecker (a1) (a2), Andrea H. Son (a3), Heba Alhmidi (a4), Brigid M. Wilson (a5), Peter M. Wiest (a1) (a2) and Curtis J. Donskey (a2) (a5)...

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