Hostname: page-component-8448b6f56d-sxzjt Total loading time: 0 Render date: 2024-04-18T07:36:04.165Z Has data issue: false hasContentIssue false

Effect of Chlorhexidine Bathing and Other Infection Control Practices on the Benefits of Universal Glove and Gown (BUGG) Trial: A Subgroup Analysis

Published online by Cambridge University Press:  24 February 2015

Daniel J. Morgan
Affiliation:
University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland
Lisa Pineles
Affiliation:
University of Maryland School of Medicine, Baltimore, Maryland
Michelle Shardell
Affiliation:
University of Maryland School of Medicine, Baltimore, Maryland
Carol Sulis
Affiliation:
Section of Infectious Diseases, Boston University School of Medicine, Boston, Massachusetts
Daniel H. Kett
Affiliation:
Department of Medicine, University of Miami Miller School of Medicine, Miami, Florida
Jason Bowling
Affiliation:
Division of Infectious Diseases, Department of Medicine, University Health System, University of Texas Health Science Center at San Antonio, San Antonio, Texas
Beverly M. Belton
Affiliation:
Yale New Haven Health System-Center for Healthcare Solutions, New Haven, Connecticut. Members of the study group are listed at the end of the text
Anthony D. Harris
Affiliation:
University of Maryland School of Medicine, Baltimore, Maryland Veterans Affairs Maryland Health Care System, Baltimore, Maryland

Abstract

We report the results of a subgroup analysis of the Benefits of Universal Glove and Gown trial. In 20 intensive care units, the reduction in acquisition of methicillin-resistant Staphylococcus aureus observed in this trial was observed in units also using chlorhexidine bathing and in those that previously performed active surveillance.

Infect Control Hosp Epidemiol 2015;00(0): 1–4

Type
Concise Communications
Copyright
© 2015 by The Society for Healthcare Epidemiology of America. All rights reserved 

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Klevens, RM, Edwards, JR, Richards, CL Jr, et al. Estimating health care-associated infections and deaths in U.S. hospitals, 2002. Public Health Rep 2007;122:160166.CrossRefGoogle ScholarPubMed
2. Cosgrove, SE, Sakoulas, G, Perencevich, EN, et al. Comparison of mortality associated with methicillin-resistant and methicillin-susceptible Staphylococcus aureus bacteremia: a meta-analysis. Clin Infect Dis 2003;36:5359.Google Scholar
3. Huskins, WC, Huckabee, CM, O’Grady, NP, et al. Intervention to reduce transmission of resistant bacteria in intensive care. N Engl J Med 2011;364:14071418.Google Scholar
4. Derde, LP, Cooper, BS, Goossens, H, et al. Interventions to reduce colonisation and transmission of antimicrobial-resistant bacteria in intensive care units: an interrupted time series study and cluster randomised trial. Lancet Infect Dis 2014;14:3139.Google Scholar
5. Milstone, AM, Elward, A, Song, X, et al. Daily chlorhexidine bathing to reduce bacteraemia in critically ill children: a multicentre, cluster-randomised, crossover trial. Lancet 2013;381:10991106.Google Scholar
6. Huang, SS, Septimus, E, Kleinman, K, et al. Targeted versus universal decolonization to prevent ICU infection. N Engl J Med 2013;368:22552265.Google Scholar
7. Harris, AD, Pineles, L, Belton, B, et al. Universal glove and gown use and acquisition of antibiotic-resistant bacteria in the ICU: a randomized trial. JAMA 2013;310:15711580.Google Scholar
8. Edmond, MB, Wenzel, RP.. Targeted decolonization to prevent ICU infections. N Engl J Med 2013;369:1471.Google ScholarPubMed