Skip to main content Accessibility help

Effect of Antiseptic Agents on Skin Flora of the Perineum of Men with Spinal Cord Injury

  • Donna S. Gilmore (a1), John Z. Montgomerie (a1), Irene E. Graham (a1), Donald G. Schick (a1) and Enes M. Jimenez (a1)...


Male patients with spinal cord injury are frequently colonized with P. aeruginosa and K. pneumoniae on the perineum. Regular bathing with bar soap has not influenced this colonization. We have attempted to remove these bacteria using antiseptic agents. The number of P. aeruginosa, K. pneumoniae and total aerobic bacteria on the perineum and the penile shaft was determined before and after cleaning with bar soap, chlorhexidine, povidone-iodine and pHresh. Povidone-iodine and chlorhexidine had no advantage over bar soap or pHresh in the removal of P. aeruginosa or K. pneumoniae from the perineum of patients with spinal cord injury.


Corresponding author

Rancho Los Amigos Hospital, 7601 East Imperial Highway, Downey, CA 90242


Hide All
1.Gilmore, DS, Bruce, SK, Jimenez, EM, et al: Pseudomonas aeruginosa colonization in patients with spinal cord injuries. J Clin Microbiol 1982; 16:856860.
2.Gilmore, DS, Schick, DG, Montgomerie, JZ: Pseudomonas aeruginosa and Klebsiella pneumoniae on the perinea of males with spinal cord injuries. J Clin Microbiol 1982;16:865867.
3.Montgomerie, JZ, Morrow, JW: Pseudomonas colonization in patients with spinal cord injury. Am J Epidemiol 1978;108:326336.
4.Montgomerie, JZ, Morrow, JW: Long-term Pseudomonas colonization in spinal cord injury patients. Am J Epidemiol 1980;112:508517.
5.Gilmore, DS, Jimenez, EM, Aeilts, GD, et al: Effects of bathing on colonization of spinal cord injury patients with Pseudomonas and Klebsiella. J Clin Microbiol 1981;14:404407.
6.Aly, R, Maibach, HI: Effect of antimicrobial soap containing Chlorhexidine on the microbial flora of skin. Appl Environ Health 1976;31:931935.
7.Bodey, GP, Ebersole, R, Hong, HC: Randomized trial of hexachlorophene preparation and P-300 bacteriostatic soaps. J Invest Dermatol 1976;67:532537.
8.Brandberg, A, Andersson, I: Preoperative whole body disinfection by shower bath with Chlorhexidine soap: Effect on transmission of bacteria from skin flora, in Maibach, HI, Aly, R (ed): Skin Microbiology: Relevance to Clinical Infection. New York, Springer-Verlag, 1981, pp 9297.
9.Davies, J, Babb, JR, Ayliffe, GAJ: The effect on the skin flora of bathing with antiseptic solutions. J Antimicrob Chemother 1977;3:473481.
10.Lilly, HA, Lowbury, EJ: Disinfection of the skin: An assessment of some new preparations. Br Med J 1971;3:674676.
11.Nielsen, ML, Raahave, D, Stage, JG, et al: Anaerobic and aerobic skin bacteria before and after skin disinfection with Chlorhexidine: An experimental study in volunteers. J Clin Pathol 1975;28:793797.
12.Voss, JG: Effects of an antibacterial soap on the ecology of aerobic bacterial flora of human skin. Applied Microbiology 1975;30:551556.
13.Byatt, ME, Henderson, A: Pre-operative sterilization of the perineum: A comparison of six antiseptics. J Clin Pathol 1973;26:921924.
14.Bruce, SK, Schick, DG, Tanaka, L, et al: A selective medium for isolation of Klebsiella pneumoniae. J Clin Microbiol 1981;13:115116.
15.Rosebury, T: Microorganisms Indigenous to Man. New York, McGraw-Hill, 1962, pp 317322.
16.Selwyn, S, Ellis, H: Skin bacteria and skin disinfection reconsidered. Br Med J 1971;1:136.


Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed