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Effect of a urine culture stewardship initiative on urine culture utilization and catheter-associated urinary tract infections in intensive care units

Published online by Cambridge University Press:  08 July 2021

Layla A. Al-Bizri Open the ORCID record for Layla A. Al-Bizri [Opens in a new window] ,
Amit T. Vahia ,
Khulood Rizvi ,
Ana C. Bardossy ,
Paula K. Robinson ,
Ryan T. Shelters ,
Susan Klotz ,
Patricia M. Starr ,
Katherine Q. Reyes  and
Geehan Suleyman
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Layla A. Al-Bizri
Affiliation:
Division of Internal Medicine, Henry Ford Health System, Detroit, Michigan
Amit T. Vahia
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan
Khulood Rizvi
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan
Ana C. Bardossy
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan
Paula K. Robinson
Affiliation:
Department of Infection Prevention and Control, Henry Ford Health System, Detroit, Michigan
Ryan T. Shelters
Affiliation:
Department of Infection Prevention and Control, Henry Ford Health System, Detroit, Michigan
Susan Klotz
Affiliation:
Department of Nursing, Henry Ford Health System, Detroit, Michigan
Patricia M. Starr
Affiliation:
Department of Infection Prevention and Control, Henry Ford Health System, Detroit, Michigan
Katherine Q. Reyes
Affiliation:
Division of Internal Medicine, Henry Ford Health System, Detroit, Michigan Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan
Geehan Suleyman
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan Department of Infection Prevention and Control, Henry Ford Health System, Detroit, Michigan
George J. Alangaden*
Affiliation:
Division of Infectious Diseases, Henry Ford Health System, Detroit, Michigan Department of Infection Prevention and Control, Henry Ford Health System, Detroit, Michigan
*
Author for correspondence: George J. Alangaden, E-mail: galanga1@hfhs.org.
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Abstract

Objective:

Urine cultures have poor specificity for catheter-associated urinary tract infections (CAUTIs). We evaluated the effect of a urine-culture stewardship program on urine culture utilization and CAUTI in adult intensive care units (ICUs).

Design:

A quasi-interventional study was performed from 2015 to 2017.

Setting and patients:

The study cohort comprised 21,367 patients admitted to the ICU at a teaching hospital.

Intervention:

The urine culture stewardship program included monthly 1-hour discussions with ICU house staff emphasizing avoidance of “pan-culture” for sepsis workup and obtaining urine culture only if a urinary source of sepsis is suspected. The urine culture utilization rate metric (UCUR; ie, no. urine cultueres/catheter days ×100) was utilized to measure the effect. Monthly UCUR, catheter utilization ratio (CUR), and CAUTI rate were reported on an interactive quality dashboard. To ensure safety, catheterized ICU patients (2015–2016) were evaluated for 30-day readmission for UTI. Time-series data and relationships were analyzed using Spearman correlation coefficients and regression analysis.

Results:

Urine culture utilization decreased from 3,081 in 2015 to 2,158 in 2016 to 1,218 in 2017. CAUTIs decreased from 78 in 2015 to 60 in 2016 and 28 in 2017. Regression analysis over time showed significant decreases in UCUR (r, 0.917; P < .0001) and CAUTI rate (r, 0.657; P < .0001). The co-correlation between UCUR and CAUTI rate was (r, 0.625; P < .0001) compared to CUR and CAUTI rate (r, 0.523; P = .004). None of these patients was readmitted with a CAUTI.

Conclusions:

Urine culture stewardship program was effective and safe in reducing UC overutilization and was correlated with a decrease in CAUTIs. Addition of urine-culture stewardship to standard best practices could reduce CAUTI in ICUs.

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 43 , Issue 8 , August 2022 , pp. 1032 - 1035
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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Footnotes

PREVIOUS PRESENTATION: Preliminary data from this study was presented as an abstract at Society for Healthcare Epidemiology of America (SHEA) Spring Conference 2017 on March 29, 2017, in St Louis, Missouri.

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