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Coronavirus disease 2019 (COVID-19) vaccine intentions and uptake in a tertiary-care healthcare system: A longitudinal study

Part of: SARS-CoV-2/COVID-19

Published online by Cambridge University Press:  27 December 2021

Charlesnika T. Evans Open the ORCID record for Charlesnika T. Evans [Opens in a new window] ,
Benjamin J. DeYoung ,
Elizabeth L. Gray ,
Amisha Wallia ,
Joyce Ho Open the ORCID record for Joyce Ho [Opens in a new window] ,
Mercedes Carnethon ,
Teresa R. Zembower Open the ORCID record for Teresa R. Zembower [Opens in a new window] ,
Lisa R. Hirschhorn Open the ORCID record for Lisa R. Hirschhorn [Opens in a new window]  and
John T. Wilkins Open the ORCID record for John T. Wilkins [Opens in a new window]
Charlesnika T. Evans*
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Center for Health Services and Outcomes Research, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Center of Innovation for Complex Chronic Healthcare, Department of Veterans’ Affairs, Edward Hines, Jr, VA Hospital, Hines, Illinois
Benjamin J. DeYoung
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Elizabeth L. Gray
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Amisha Wallia
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Center for Health Services and Outcomes Research, Institute for Public Health and Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Division of Endocrinology, Metabolism, and Molecular Medicine, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Joyce Ho
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Mercedes Carnethon
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Teresa R. Zembower
Affiliation:
Division of Infectious Diseases, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Division of Microbiology, Department of Pathology, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
Lisa R. Hirschhorn
Affiliation:
Department of Medical Social Sciences, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
John T. Wilkins
Affiliation:
Department of Preventive Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois Division of Cardiology, Department of Medicine, Feinberg School of Medicine, Northwestern University, Chicago, Illinois
*
Author for correspondence: Charlesnika T. Evans, E-mail: charlesnika-evans@northwestern.edu
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Abstract

Objectives:

Healthcare workers (HCWs) are a high-priority group for coronavirus disease 2019 (COVID-19) vaccination and serve as sources for public information. In this analysis, we assessed vaccine intentions, factors associated with intentions, and change in uptake over time in HCWs.

Methods:

A prospective cohort study of COVID-19 seroprevalence was conducted with HCWs in a large healthcare system in the Chicago area. Participants completed surveys from November 25, 2020, to January 9, 2021, and from April 24 to July 12, 2021, on COVID-19 exposures, diagnosis and symptoms, demographics, and vaccination status.

Results:

Of 4,180 HCWs who responded to a survey, 77.1% indicated that they intended to get the vaccine. In this group, 23.2% had already received at least 1 dose of the vaccine, 17.4% were unsure, and 5.5% reported that they would not get the vaccine. Factors associated with intention or vaccination were being exposed to clinical procedures (vs no procedures: adjusted odds ratio [AOR], 1.39; 95% confidence interval [CI], 1.16–1.65) and having a negative serology test for COVID-19 (vs no test: AOR, 1.46; 95% CI, 1.24–1.73). Nurses (vs physicians: AOR, 0.24; 95% CI, 0.17–0.33), non-Hispanic Black (vs Asians: AOR, 0.35; 95% CI, 0.21–0.59), and women (vs men: AOR, 0.38; 95% CI, 0.30–0.50) had lower odds of intention to get vaccinated. By 6-months follow-up, >90% of those who had previously been unsure were vaccinated, whereas 59.7% of those who previously reported no intention of getting vaccinated, were vaccinated.

Conclusions:

COVID-19 vaccination in HCWs was high, but variability in vaccination intention exists. Targeted messaging coupled with vaccine mandates can support uptake.

Type
Original Article
Information
Infection Control & Hospital Epidemiology , Volume 43 , Issue 12 , December 2022 , pp. 1806 - 1812
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Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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