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Comparison of the Duration of Antimicrobial Activity of 2 Different Antimicrobial Central Venous Catheters

  • Theofilos Matheos (a1), J. Matthias Walz (a1) (a2), Janice P. Adams (a1), Karen Johnson (a1), Karen Longtine (a1), Jaclyn Longtine (a1), Melissa O'Neill (a1) and Stephen O. Heard (a1) (a2)...


We compared the duration of antimicrobial effectiveness of 2 different antimicrobial catheters. The baseline activity of minocycline-rifampin catheters was greater than that of silver-platinum-carbon catheters against Staphylococcus aureus, Staphylococcus epidermidis, and Enterococcus faecalis. The antimicrobial activity of the minocycline-rifampin catheters against these pathogens persisted for up to 12 days, while that of the silver-platinum-carbon catheters was depleted by day 10 (P< .05).


Corresponding author

Department of Anesthesiology, University of Massachusetts Medical School, 55 Lake Avenue North, Worcester, MA 01655 (


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