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Clinical Significance of Low Colony-Count Urine Cultures Among Hospitalized Inpatients

  • Marc-André Smith (a1) (a2), Michael J. Lamb (a3), Laura Baillie (a2), Andrew Simor (a2) (a4) (a3) and Jerome A. Leis (a1) (a4) (a3)...


Corresponding author

Address correspondence to Marc-André Smith, MD, MSc, Sunnybrook Health Sciences Centre, 2075 Bayview Avenue, Toronto, Ontario M4N 3M5 (


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1. McCarter, YS, Burd, EM, Hall, GS, Zervos, M. Cumitech 2C: Laboratory Diagnosis of Urinary Tract Infections. Washington, DC: ASM Press; 2009.
2. Stamm, WE, Counts, GW, Running, KR, Fihn, S, Turck, M, Holmes, KK. Diagnosis of coliform infection in acutely dysuric women. N Engl J Med 1982;307:463468.
3. Hooton, TM, Robert, PL, Cox, ME, Stapleton, AE. Voided midstream urine culture and acute cystitis in premenopausal women. N Engl J Med 2013;369:18831891.
4. Kass, EH. Bacteriuria and the diagnosis of infections of the urinary tract with observations on the use of methionine as a urinary antiseptic. AMA Arch Intern Med 1957;100:709714.
5. Leis, JA, Rebick, GW, Daneman, N, et al. Reducing antimicrobial therapy for asymptomatic bacteriuria among noncatheterized inpatients: a proof-of-concept study. Clin Infect Dis 2014;58:980983.
6. Nicolle, LE, Bradley, S, Colgan, R, et al. Infectious Diseases Society of America guidelines for the diagnosis and treatment of asymptomatic bacteriuria in adults. Clin Infect Dis 2005;50:643654.
7. National Healthcare Safety Network (NHSN) patient safety component manual. Centers for Disease Control and Prevention website. Published 2017. Accessed January 8, 2018.
8. Kwon, JH, Fausone, MK, Du, H, Robicsek, A, Peterson, LR. Impact of laboratory reported urine culture colony counts on the diagnosis and treatment of urinary tract infection for hospitalized patients. Am J Clin Pathol 2012;137:778784.
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Infection Control & Hospital Epidemiology
  • ISSN: 0899-823X
  • EISSN: 1559-6834
  • URL: /core/journals/infection-control-and-hospital-epidemiology
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