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The burden of colonization and infection by carbapenemase-producing Enterobacteriaceae in the neuro-rehabilitation setting: a prospective six-year experience

  • Sara Tedeschi (a1), Filippo Trapani (a1), Annalisa Liverani (a2), Fabio Tumietto (a1), Francesco Cristini (a1), Salvatore Pignanelli (a3), Andrea Berlingeri (a4), Jacopo Bonavita (a2), Gian Piero Belloni (a2), Michele Bartoletti (a1), Maddalena Giannella (a1), Roberto Pederzini (a2) and Pierluigi Viale (a1)...

Abstract

We describe the high burden of carbapenemase-producing Enterobacteriaceae (CPE) colonization and infection in a neuro-rehabilitation hospital in Italy over a 6-year period. Overall, 9.3% of patients were found to be CPE carriers on admission; the rates of CPE in-hospital acquisition and CPE-BSI were 9.2 and 2.9 cases per 10,000 patient days, respectively.

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Corresponding author

Author for correspondence: Sara Tedeschi, Email: sara.tedeschi@aosp.bo.it

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PREVIOUS PRESENTATION: The data reported in this article were presented in part as an oral presentation during the 27th European Congress of Clinical Microbiology and Infectious Diseases, April 24 2017, in Vienna, Austria.

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1.Hayden, MK, Lin, MY, Lolans, K, et al. Prevention of colonization and infection by Klebsiella pneumoniae carbapenemase-producing Enterobacteriaceae in long-term acute-care hospitals. Clin Infect Dis 2015;60:11531161.
2.Morgan, DJ, Diekema, DJ, Sepkowitz, K, Perencevich, EN. Adverse outcomes associated with contact precautions: a review of the literature. Am J Infect Control 2009;37:8593.
3.Tedeschi, S, Trapani, F, Giannella, M, et al. An antimicrobial stewardship program based on systematic infectious disease consultation in a rehabilitation facility. Infect Control Hosp Epidemiol 2017;38:7682.
4.Pignanelli, S, Zaccherini, P, Schiavone, P, Nardi Pantoli, A, Pirazzoli, S, Nannini, R. In vitro antimicrobial activity of several antimicrobial agents against Escherichia coli isolated from community-acquired uncomplicated urinary tract infections. Eur Rev Med Pharmacol Sci 2013;17:206209.
5.Viale, P, Tumietto, F, Giannella, M, et al. Impact of a hospital-wide multifaceted program for reducing carbapenem-resistant Enterobacteriaceae infections in a large teaching hospital in northern Italy. Clin Microbiol Infect 2015;21:242247.
6.Agodi, A, Voulgari, E, Barchitta, M, et al. Containment of an outbreak of KPC-3-producing Klebsiella pneumoniae in Italy. J Clin Microbiol 2011;49:39863989.
7.Munoz-Price, LS, Poirel, L, Bonomo, RA, et al. Clinical epidemiology of the global expansion of Klebsiella pneumoniae carbapenemases. Lancet Infect Dis 2013;13:785796.
8.Okamoto, K, Lin, MY, Haverkate, M, et al. Modifiable risk factors for the spread of Klebsiella pneumoniae carbapenemase-producing enterobacteriaceae among long-term acute-care hospital patients. Infect Control Hosp Epidemiol 2017;38:670677.
9.Singh, K, Mangold, KA, Wyant, K, et al. Rectal screening for Klebsiella pneumoniae carbapenemases: comparison of real-time PCR and culture using two selective screening agar plates. J Clin Microbiol 2012;50:2596–600.

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