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Association between negative-pressure room utilization and hospital-acquired Aspergillus rates in patients with coronavirus disease 2019 (COVID-19) in two academic hospitals

Published online by Cambridge University Press:  23 June 2023

Brett M. Biebelberg*
Affiliation:
Department of Emergency Medicine, Massachusetts General Hospital, Boston, Massachusetts Sidney Kimmel Medical College, Philadelphia, Pennsylvania
Shangyuan Ye
Affiliation:
Biostatistics Shared Resource, Knight Cancer Institute, Oregon Health and Science University, Portland, Oregon
Rui Wang
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts
Michael Klompas
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
Chanu Rhee
Affiliation:
Department of Population Medicine, Harvard Medical School and Harvard Pilgrim Health Care Institute, Boston, Massachusetts Division of Infectious Diseases, Department of Medicine, Brigham and Women’s Hospital, Boston, Massachusetts
*
Corresponding author: Brett M. Biebelberg; Email: bbiebelberg@mgh.harvard.edu

Abstract

Hospital-acquired Aspergillus rates among coronavirus disease 2019 (COVID-19) patients were initially higher at a hospital with high negative-pressure room utilization compared to a similar hospital with low utilization but with otherwise identical infection control policies. After the index hospital decreased negative-pressure utilization, hospital-acquired Aspergillus case rates at the 2 hospitals converged.

Type
Concise Communication
Copyright
© The Author(s), 2023. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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