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An Outbreak of Pyodermas Among Neonates Caused by Ultrasound Gel Contaminated With Methicillin-Susceptible Staphylococcus Aureus

  • Klaus Weist (a1), Constanze Wendt (a1), Lyle R. Petersen (a2), Hans Versmold (a3) and Henning Rüden (a1)...



To investigate an outbreak of methicillin-susceptible Staphylococcus aureus (MSSA); infections in a neonatal clinic.


Prospective chart review, environmental sampling, and genotyping by two independent methods: pulsed-field gel electrophoresis (PFGE) and randomly amplified polymorphic DNA polymerase chain reaction (RAPD-PCR). A case-control study was performed with 31 controls from the same clinic.


A German 1,350-bed tertiary-care teaching university hospital.


There was a significant increase in the incidence of pyodermas with MSSA 10 neonates in good physical condition with no infection immediately after birth developed pyodermas. A shared spatula and ultrasound gel were the only identified infection sources. The gel contained MSSA and was used for hip-joint sonographies in all neonates. PFGE and RAPD-PCR patterns from 6 neonates and from the gel were indistinguishable and thus genetically related clones. The case-control study revealed no significant risk factor with the exception of cesarean section (P=.006). The attack rate by days of hip-joint sonography between April 15 and April 27, 1994, was 11.8% to 40%.


Inappropriate hygienic measures in connection with lubricants during routine ultrasound scanning may lead to nosocomial S aureus infections of the skin. To our knowledge this source of S aureus infections has not previously been described.


Corresponding author

Institut für Hygiene, Freie Universität Berlin, Universitätsklinikum Benjamin Franklin, Hindenburgdamm 27, 12203 Berlin, Germany


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An Outbreak of Pyodermas Among Neonates Caused by Ultrasound Gel Contaminated With Methicillin-Susceptible Staphylococcus Aureus

  • Klaus Weist (a1), Constanze Wendt (a1), Lyle R. Petersen (a2), Hans Versmold (a3) and Henning Rüden (a1)...


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