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An Observational Study to Compare Oral Hygiene Care With Chlorhexidine Gluconate Gel Versus Mouthwash to Prevent Ventilator-Associated Pneumonia

  • Hung-Jen Tang (a1) (a2), Chien-Ming Chao (a3), Pak-On Leung (a3) and Chih-Cheng Lai (a3)
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Abstract

Copyright

Corresponding author

Address correspondence to Chih-Cheng Lai, Department of Intensive Care Medicine, Chi-Mei Medical Center, Liouying, Tainan, Taiwan (dtmed141@gmail.com).

References

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1. Guillamet, CV, Kollef, MH. Update on ventilator-associated pneumonia. Curr Opin Crit Care 2015;21:430438.
2. Guillamet, CV, Kollef, MH. Ventilator-associated pneumonia in the ICU: where has it gone? Curr Opin Pulm Med 2015;21:226231.
3. O’Grady, NP, Murray, PR, Ames, N. Preventing ventilator-associated pneumonia: does the evidence support the practice? JAMA 2012;307:25342539.
4. Chen, Y, Mao, EQ, Yang, YJ, et al. Prospective observational study to compare oral topical metronidazole versus 0.2% chlorhexidine gluconate to prevent nosocomial pneumonia. Am J Infect Control 2016;44:11161122.
5. Zhang, TT, Tang, SS, Fu, LJ. The effectiveness of different concentrations of chlorhexidine for prevention of ventilator-associated pneumonia: a meta-analysis. J Clin Nurs 2014;23:14611475.
6. Cocanour, CS, Peninger, M, Domonoske, BD, et al. Decreasing ventilator-associated pneumonia in a trauma ICU. J Trauma 2006;61:122129; discussion 129–130.
7. Hua, F, Xie, H, Worthington, HV, et al. Oral hygiene care for critically ill patients to prevent ventilator-associated pneumonia. Cochrane Database Syst Rev 2016;10:Cd008367.
8. Fourrier, F, Dubois, D, Pronnier, P, et al. Effect of gingival and dental plaque antiseptic decontamination on nosocomial infections acquired in the intensive care unit: a double-blind placebo-controlled multicenter study. Crit Care Med 2005;33:17281735.
9. Francis, JR, Hunter, B, Addy, M. A comparison of three delivery methods of chlorhexidine in handicapped children. I. Effects on plaque, gingivitis, and toothstaining. J Periodontol 1987;58:451455.

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