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An Investigation of the Bactericidal Effect of Certain Antiseptics and Disinfectants on Some Hospital Isolates of Gram-Negative Bacteria

Published online by Cambridge University Press:  02 January 2015

Melike Tunçay Ekizoglu
Affiliation:
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey
Meral Özalp*
Affiliation:
Department of Pharmaceutical Microbiology, Faculty of Pharmacy, Hacettepe University, Ankara, Turkey
Nedim Sultan
Affiliation:
Department of Medical Microbiology, Faculty of Medicine, Gazi University, Ankara, Turkey
Deniz Gür
Affiliation:
Ihsan Dogramaci Children's Hospital, Clinical Microbiology Laboratory, Hacettepe University, Ankara, Turkey
*
Hacettepe University, Faculty of Pharmacy, Department of Pharmaceutical Microbiology, 06100 Ankara, Turkey

Abstract

The effect of widely used antiseptics and disinfectants on some hospital isolates of gram-negative bacteria was assessed by the quantitative suspension test. Chlorhexidine gluconate (4%), savlon (1:100), and 5.25% sodium hypochlorite were tested. Savlon and chlorhexidine gluconate were effective at in-use concentrations and sodium hypochlorite was effective at 1:50 dilution.

Type
Concise Communications
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2003

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References

1.Griffiths, PA, Babb, JR, Bradley, CR, Fraise, ARGlutaraldehyde-resistant Mycobacterium chelonae from endoscope washer disinfectors. J Appl Microbiol 1997;82:519526.CrossRefGoogle ScholarPubMed
2.Russell, AD, Day, MJ. Antibacterial activity of Chlorhexidine. J Hosp Infect 1993;25:229238.CrossRefGoogle ScholarPubMed
3.Wolf, AA. Anhydrous sodium thiosulfate as a primary iodometric standard. Anal Chem 1982;54:21342136.CrossRefGoogle Scholar
4.Rutala, W, Weber, DJ. Uses of inorganic hypochlorite (bleach) in healthcare facilities. Clin Microbiol Rev 1997;10:597610.CrossRefGoogle Scholar
5.Coates, D, Hutchinson, DN. How to produce a hospital disinfection policy. J Hosp Infect 1994;26:5768.CrossRefGoogle ScholarPubMed
6.Reybrouck, G. A comparison of the quantitative suspension tests for the assessment of disinfectants. Zbl Bad Hygl Abt Orig B 1980;170:449456.Google ScholarPubMed
7.Bloomfield, SF, Arthur, M, Looney, E, Begun, K, Patel, H. Comparative testing of disinfectant and antiseptic products using proposed European suspension testing methods. Lett Appl Microbiol 1991;13:233237.CrossRefGoogle Scholar
8.Hammond, SA, Morgan, JR, Russell, AD. Comparative susceptibility of hospital isolates of gram-negative bacteria to antiseptics and disinfectants. J Hosp Infect 1987;9:255264.CrossRefGoogle ScholarPubMed
9.Payne, DN, Babb, JR, Bradley, CR. An evaluation of the European suspension test to reflect in vitro activity of antiseptics against clinically significant organisms. Lett Appl Microbiol 1999;28:712.CrossRefGoogle ScholarPubMed
10.Sagripanti, JL, Eklund, CA, Trost, PA, et al.Comparative sensitivity of 13 species of pathogenic bacteria to seven chemical germicides. Am J Infect Control 1997;25:335339.CrossRefGoogle ScholarPubMed
11.Rutala, WA, Cole, CC, Thomann, CA, Weber, DJ. Stability and bactericidal activity of chlorine solutions. Infect Control Hosp Epidemiol 1998;19:323327.CrossRefGoogle ScholarPubMed