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Post-discharge decolonization of patients harboring methicillin-resistant Staphylococcus aureus (MRSA) USA300 strains: secondary analysis of the CLEAR Trial

Published online by Cambridge University Press:  16 December 2021

Gabrielle M. Gussin*
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
Lauren Heim
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
Thomas Tjoa
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
James A. McKinnell
Affiliation:
Infectious Diseases, Lundquist Institute, Harbor-UCLA Medical Center, Torrance, CA, USA
Loren G. Miller
Affiliation:
Infectious Diseases, Lundquist Institute, Harbor-UCLA Medical Center, Torrance, CA, USA
Daniel L. Gillen
Affiliation:
Statistics, University of California, Irvine, Irvine, CA, USA
Mohamad R.A. Sater
Affiliation:
Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, MA, USA
Yonatan H. Grad
Affiliation:
Immunology and Infectious Diseases, Harvard TH Chan School of Public Health, Boston, MA, USA
Raveena D. Singh
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
Susan S. Huang
Affiliation:
Infectious Diseases, University of California, Irvine School of Medicine, Irvine, CA, USA
*
Author for correspondence: Gabrielle M. Gussin, E-mail: gussing@hs.uci.edu

Abstract

The CLEAR Trial recently found that decolonization reduced infections and hospitalizations in MRSA carriers in the year following hospital discharge. In this secondary analysis, we explored whether decolonization had a similar benefit in the subgroup of trial participants who harbored USA300, using two different definitions for the USA300 strain-type.

Type
Concise Communication
Copyright
© The Author(s), 2021. Published by Cambridge University Press on behalf of The Society for Healthcare Epidemiology of America

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References

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