Skip to main content Accessibility help
×
Home
Hostname: page-component-559fc8cf4f-6f8dk Total loading time: 0.4 Render date: 2021-02-25T17:46:43.231Z Has data issue: true Feature Flags: { "shouldUseShareProductTool": true, "shouldUseHypothesis": true, "isUnsiloEnabled": true, "metricsAbstractViews": false, "figures": false, "newCiteModal": false, "newCitedByModal": true }

Efficacy of a stewardship intervention focused on reducing unnecessary use of non–Clostridioides difficile antibiotics in patients with Clostridioides difficile infection

Published online by Cambridge University Press:  17 December 2019

Michelle T. Hecker
Affiliation:
Division of Infectious Diseases, MetroHealth Medical Center, Cleveland, Ohio Case Western Reserve University School of Medicine, Cleveland, Ohio
Andrea H. Son
Affiliation:
Department of Pharmacy, MetroHealth Medical Center, Cleveland, Ohio
Heba Alhmidi
Affiliation:
Research Service, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Brigid M. Wilson
Affiliation:
Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Peter M. Wiest
Affiliation:
Division of Infectious Diseases, MetroHealth Medical Center, Cleveland, Ohio Case Western Reserve University School of Medicine, Cleveland, Ohio
Curtis J. Donskey
Affiliation:
Case Western Reserve University School of Medicine, Cleveland, Ohio Geriatric Research, Education, and Clinical Center, Louis Stokes Cleveland VA Medical Center, Cleveland, Ohio
Corresponding
E-mail address:

Abstract

In a tertiary-care hospital and affiliated long-term care facility, a stewardship intervention focused on patients with Clostridioides difficile infection (CDI) was associated with a significant reduction in unnecessary non-CDI antibiotic therapy. However, there was no significant reduction in total non-CDI therapy or in the frequency of CDI recurrence.

Type
Concise Communication
Copyright
© 2019 by The Society for Healthcare Epidemiology of America. All rights reserved.

Access options

Get access to the full version of this content by using one of the access options below.

References

Pop-Vicas, A, Shaban, E, Letourneau, C, Pechie, A.Empirical antimicrobial prescriptions in patients with Clostridium difficile infection at hospital admission and impact on clinical outcomes. Infect Control Hosp Epidemiol 2012;33:11011106.10.1086/668015CrossRefGoogle Scholar
Shaughnessy, MK, Amundson, WH, Kuskowski, MA, DeCarolis, DD, Johnson, JR, Drekonja, DM.Unnecessary antimicrobial use in patients with current or recent Clostridium difficile infection. Infect Control Hosp Epidemiol 2013;34:109116.10.1086/669089CrossRefGoogle ScholarPubMed
Watson, RL, Graber, CJ.Lack of improvement in antimicrobial prescribing after a diagnosis of Clostridium difficile and impact on recurrence. Am J Infect Control 2018;46:13701374.10.1016/j.ajic.2018.04.213CrossRefGoogle ScholarPubMed
Graber, CJ, Madaras-Kelly, K, Jones, MM, Neuhauser, MM, Goetz, MB.Unnecessary antimicrobial use in the context of Clostridium difficile infection: a call to arms for the Veterans’ Affairs Antimicrobial Stewardship Task Force. Infect Control Hosp Epidemiol 2013;34:651653.10.1086/670640CrossRefGoogle Scholar
Buckel, WR, Avdic, E, Carroll, KC, Gunaseelan, V, Hadhazy, E, Cosgrove, SE.Gut check: Clostridium difficile testing and treatment in the molecular testing era. Infect Control Hosp Epidemiol 2015;36:217221.10.1017/ice.2014.19CrossRefGoogle ScholarPubMed
Jury, LA, Tomas, M, Kundrapu, S, Sitzlar, B, Donskey, CJ.A Clostridium difficile infection (CDI) stewardship initiative improves adherence to practice guidelines for management of CDI. Infect Control Hosp Epidemiol 2013;34:12221224.10.1086/673459CrossRefGoogle ScholarPubMed
Hecker, MT, Ho, E, Donskey, CJ.Fear of failure: engaging patients in antimicrobial stewardship after fecal transplantation for recurrent Clostridium difficile infection. Infect Control Hosp Epidemiol 2017;38:127129.10.1017/ice.2016.236CrossRefGoogle ScholarPubMed
Cohen, SH, Gerding, DN, Johnson, S, et al.Clinical practice guidelines for Clostridium difficile infection in adults: 2010 update by the society for healthcare epidemiology of America (SHEA) and the infectious diseases society of America (IDSA). Infect Control Hosp Epidemiol 2010;31:431455.10.1086/651706CrossRefGoogle Scholar
Hecker, MT, Aron, DC, Patel, NP, Lehmann, MK, Donskey, CJ.Unnecessary use of antimicrobials in hospitalized patients. Arch Intern Med 2003;163:972978.10.1001/archinte.163.8.972CrossRefGoogle ScholarPubMed
Hecker, MT, Son, AH, Murphy, NN, et al.Impact of syndrome-specific antimicrobial stewardship interventions on use of and resistance to fluoroquinolones: An interrupted time series analysis. Am J Infect Control 2019;47:869875.CrossRefGoogle ScholarPubMed

Hecker et al. supplementary material

Table S1

File 14 KB

Altmetric attention score

Full text views

Full text views reflects PDF downloads, PDFs sent to Google Drive, Dropbox and Kindle and HTML full text views.

Total number of HTML views: 58
Total number of PDF views: 100 *
View data table for this chart

* Views captured on Cambridge Core between 17th December 2019 - 25th February 2021. This data will be updated every 24 hours.

Send article to Kindle

To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

Find out more about the Kindle Personal Document Service.

Efficacy of a stewardship intervention focused on reducing unnecessary use of non–Clostridioides difficile antibiotics in patients with Clostridioides difficile infection
Available formats
×

Send article to Dropbox

To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

Efficacy of a stewardship intervention focused on reducing unnecessary use of non–Clostridioides difficile antibiotics in patients with Clostridioides difficile infection
Available formats
×

Send article to Google Drive

To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

Efficacy of a stewardship intervention focused on reducing unnecessary use of non–Clostridioides difficile antibiotics in patients with Clostridioides difficile infection
Available formats
×
×

Reply to: Submit a response


Your details


Conflicting interests

Do you have any conflicting interests? *