Hostname: page-component-7479d7b7d-t6hkb Total loading time: 0 Render date: 2024-07-12T01:36:47.377Z Has data issue: false hasContentIssue false

Blood Products: A Significant Risk Factor for Long-Term Catheter-Related Bloodstream Infections in Cancer Patients

Published online by Cambridge University Press:  02 January 2015

Hend A. Hanna
Affiliation:
University of Texas M.D. Anderson Cancer Center, Section of Infection Control, Houston, Texas
Issam Raad*
Affiliation:
University of Texas M.D. Anderson Cancer Center, Section of Infection Control, Houston, Texas
*
The University of Texas M.D. Anderson Cancer Center, 1515 Holcombe Blvd, Houston, TX 77030

Abstract

Data obtained from a previous prospective randomized study in cancer patients conducted at our institution were analyzed to investigate risk factors for catheter-related (CR) bloodstream infections (BSIs). Our recent analysis showed that the administration of blood products through central venous catheters was a risk factor for CR BSI, whereas thrombocytopenia during catheterization may have provided protection against CR BSI, as did central venous catheter insertion under maximal sterile barrier precautions.

Type
Concise Communication
Copyright
Copyright © The Society for Healthcare Epidemiology of America 2001

Access options

Get access to the full version of this content by using one of the access options below. (Log in options will check for institutional or personal access. Content may require purchase if you do not have access.)

References

1. Raad, II, Hohn, DC, Gilbreath, J, Suleiman, N, Hill, LA, Bruso, PA, et al. Prevention of central venous catheter-related infections by using maximal sterile barrier precautions during insertion. Infect Control Hosp Epidemiol 1994;15:231238.CrossRefGoogle ScholarPubMed
2. Pearson, ML. The Hospital Infection Control Practices Advisory Committee. Guideline for prevention of intravascular device-related infections. Infect Control Hosp Epidemiol 1996;17:438473.Google Scholar
3. Howell, PB, Walters, PE, Donowitz, GR, Farr, BM. Risk factors for infection of adult patients with cancer who have tunneled central venous catheters. Cancer 1995;75:13671375.3.0.CO;2-Z>CrossRefGoogle Scholar
4. Groeger, JS, Lucas, AB, Thaler, HT, Friedlander-Klar, H, Brown, AE, Kiehn, TE, et al. Infectious morbidity associated with long-term use of venous access devices in patients wim cancer. Ann Intern Med 1993;119:11681174.Google Scholar
5. Raad, I, Davis, S, Becker, M, Hohn, D, Houston, D, Umphrey, J, et al. Low infection rate and long durability of nontunneled silastic catheters: a safe and cost-effective alternative for long-term venous access. Arch Intern Med 1993;153:17911796.CrossRefGoogle ScholarPubMed
6. Hermann, M, Lai, QJ, Albrecht, RM, Mosher, DF, Proctor, RA. Adhesion of Staphylococcus aureus to surface-bound platelets: role of fibrinogen/fibrin and platelet integrins. J Infect Dis 1992;167:312322.Google Scholar
7. Raad, I, Buzaid, A, Rhyne, J, Hachem, R, Darouiche, R, Safar, H, et al. Minocycline and ethylenediamine-tetraacetate for the prevention of recurrent vascular catheter infections. Clin Infect Dis 1997;25:149151.Google Scholar