Hostname: page-component-77c89778f8-fv566 Total loading time: 0 Render date: 2024-07-20T01:26:30.676Z Has data issue: false hasContentIssue false
  • English
  • Français

Variance component analysis for viability in an isolated population of Drosophila melanogaster*

Published online by Cambridge University Press:  14 April 2009

Hidenori Tachida ,
Muneo Matsuda ,
Shin-Ichi Kusakabe  and
Terumi Mukai
Hidenori Tachida
Affiliation:
Department of Biology, Kyushu University 33, Fukuoka 812, Japan
Muneo Matsuda
Affiliation:
Department of Biology, Kyushu University 33, Fukuoka 812, Japan
Shin-Ichi Kusakabe
Affiliation:
Department of Biology, Kyushu University 33, Fukuoka 812, Japan
Terumi Mukai*
Affiliation:
Department of Biology, Kyushu University 33, Fukuoka 812, Japan
*
‡ To whom correspondence should be addressed.

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

Using the 602 second chromosome lines extracted from the Ishigakijima population of Drosophila melanogaster in Japan, partial diallel cross experiments (Design II of Comstock & Robinson, 1952) were carried out, and the additive genetic variance and the dominance variance of viability were estimated. The estimated value of the additive genetic variance is 0·01754±0·00608, and the dominance variance 0·00151±0·00114, using a logarithmic scale. Since the value of the additive genetic variance is much larger than expected under mutation–selection balance although the dominance variance is compatible with it, we speculate that in the Ishigakijima population some type of balancing selection must be operating to maintain the genetic variability with respect to viability at a minority of loci. As candidates for such selection, overdominance, frequency-dependent selection, and diversifying selection are considered, and it is suggested that diversifying selection is the most probable candidate for increasing the additive genetic variance.

Type
Research Article
Information
Genetics Research , Volume 42 , Issue 2 , October 1983 , pp. 207 - 217
Copyright
Copyright © Cambridge University Press 1983

Footnotes

*

Paper no. 17 from the Laboratory of Population Genetics, Faculty of Science, Kyushu University 33, Fukuoka, Japan.

References

REFERENCES

Cardellino, R. A. & Mukai, T. (1975). Mutator factors and genetic variance components of viability in Drosophila melanogaster. Genetics 80, 567–583.CrossRefGoogle ScholarPubMed
Cockerham, C. C. & Weir, B. S. (1977). Quadratic analyses of reciprocal crosses. Biometrics 33, 187–203.CrossRefGoogle ScholarPubMed
Comstock, R. A. & Robinson, H. F. (1952). Estimation of average dominance of genes. In Heterosis (ed. Gowen, J. W.), pp. 494–516. Ames: Iwoa State College Press.Google Scholar
Dobzhansky, TH. (1970) Genetics of the Evolutionary Process. New York and London: Columbia University Press.Google Scholar
Dobzhansky, TH. & Spassky, B. (1963). Genetics of natural populations. XXXIV. Adaptive norm, genetic load, and genetic elite in Drosophila melanogaster. Genetics 48, 1467–1485.CrossRefGoogle Scholar
Gillespie, J. H. & Langley, C. (1974). A general model to account for enzyme variation in natural populations. Genetics 76, 837–848.CrossRefGoogle ScholarPubMed
Greenberg, R. & Crow, J. F. (1960). A comparison of the effect of lethal and detrimental chromosomes from Drosophila populations. Genetics 45, 1154–1168.CrossRefGoogle ScholarPubMed
Kidwell, M. G. (1979). Hybrid dysgenesis in Drosophila melanogaster: the relationship between the P-M and I-R interaction systems. Genetical Research 33, 205–217.CrossRefGoogle Scholar
Kidwell, M. G., Kidwell, J. F. & Sved, J. A. (1977). Hybrid dysgenesis in Drosophila melanogaster: a syndrome of aberrant traits including mutation, sterility and male recombination. Genetics 92, 813–833.CrossRefGoogle Scholar
Levene, H. (1953). Genetic equilibrium when more than one ecological niche is available. American Naturalist 87, 331–333.CrossRefGoogle Scholar
Marinkovic, D. (1967). Genetic loads affecting fecundity in natural populations of Drosophila melanogaster. Genetics 56, 61–71.CrossRefGoogle Scholar
Morton, N. E., Crow, J. F. & Muller, H. J. (1956). An estimate of the mutational damage in man from data on consanguineous marriages. Proceedings of the National Academy of Sciences, U.S.A. 42, 855–863.CrossRefGoogle ScholarPubMed
Mukai, T. (1964). The genetic structure of natural populations of Drosophila melanogaster. I. Spontaneous mutation rate of polygenes controlling viability. Genetics 50, 1–19.CrossRefGoogle ScholarPubMed
Mukai, T. (1969). The genetic structure of natural populations of Drosophila melanogaster. VIII. Natural selection on the degree of dominance of viability polygenes. Genetics 63, 467–478.Google Scholar
Mukai, T. (1977). Genetic variance for viability and linkage disequilibrium in natural populations of Drosophila melanogaster. In Measuring Selection in Natural Populations (ed. Christiansen, F. B. and Fenchell, T. M.), pp. 97–112.CrossRefGoogle Scholar
Mukai, T. (1980). The genetic structure of natural populations of Drosophila melanogaster. XIV. Effects of the incomplete dominance of the In(2LR)SM1(Cy) chromosome on estimates of various genetic parameters. Genetics 94, 169–184.CrossRefGoogle ScholarPubMed
Mukai, T., Cardellino, R. A., Watanabe, T. K. & Crow, J. F. (1974). The genetic variance for viability and its components in a local population of Drosophila melanogaster. Genetics 78, 1195–1208.CrossRefGoogle Scholar
Mukai, T., Chigusa, S. I., Mettler, L. E. & Crow, J. F. (1972). Mutation rate and dominance of genes affecting viability in Drosophila melanogaster. Genetics 72, 335–355.CrossRefGoogle ScholarPubMed
Mukai, T., Kusakabe, S. & Tachida, H. (1983). Indirect negative evidence for frequency-dependent selection with respect to viability in Drosophila melanogaster. Japanese Journal of Genetics 58, 297–314.Google Scholar
Mukai, T. & Nagano, S. (1983). The genetic structure of natural populations of Drosophila melanogaster. XVI. Excess of additive genetic variance of viability. Genetics (In the Press.)Google Scholar
Mukai, T., Tachida, H. & Ichinose, M. (1980). Selection for viability at loci controlling protein polymorphisms in Drosophila melanogaster is very weak at most. Proceedings of the National Academy of Sciences U.S.A. 77, 4857–4860.Google Scholar
Mukai, T. & Yamaguchi, O. (1974). The genetic structure of natural populations of Drosophila melanogaster. XI. Genetic variability in a local population. Genetics 76, 339–366.CrossRefGoogle Scholar
Mukai, T., Yamaguchi, O., Kusakabe, S., Tachida, H., Matsuda, M., Ichinose, M. & Yoshimaru, H. (1982). Lack of balancing selection for protein polymorphisms. In Molecular Evolution, Protein Polymorphism and the Neutral Theory (ed. Kimura, M.), pp. 81–120. Tokyo: Japan Scientific Societies Press.Google Scholar
Mukai, T. & Yamazaki, T. (1968). The genetic structure of natural populations of Drosophila melanogaster. V. Coupling-repulsion effect of spontaneous mutant polygenes controlling viability. Genetics 59, 513–535.Google Scholar
Simmons, M. J., Preston, C. R. & Engels, W. R. (1980). Pleiotropic effects on fitness of mutations affecting viability in Drosophila melanogaster. Genetics 94, 467–475.Google Scholar
Wallace, B. (1956). Studies on irradiated populations of Drosophila melanogaster. Journal of Genetics 54, 280–293.Google Scholar
Watanabe, T. K. & Ohnishi, S. (1975). Genes affecting productivity in natural populations of Drosophila melanogaster. Genetics 80, 807–819.Google Scholar
Wright, S. (1931). Evolution in Mendelian populations. Genetics 16, 97–159.CrossRefGoogle ScholarPubMed
Yamaguchi, O., Ichinose, M., Matsuda, M. & Mukai, T. (1980). Linkage disequilibrium in isolated populations of Drosophila melanogaster. Genetics 96, 507–522.Google Scholar
Yamaguchi, O. & Mukai, T. (1974). Variation of spontaneous occurrence rates of chromosomal aberrations in the second chromosomes of Drosophila melanogaster. Genetics 78, 1209–1221.Google Scholar