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Regressions between relatives

Published online by Cambridge University Press:  14 April 2009

M. G. Bulmer
M. G. Bulmer
Affiliation:
Department of Biomathematics, Pusey Street, Oxford

Summary

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A metric character determined by a large number of loci without epistasis is normally distributed. In the absence of linkage the joint distribution in two or more relatives is multivariate normal, so that all regressions are linear and have constant residual variance. In the presence of linkage this is no longer true except in the case of parent and child; for all other types of relatives the regression line is unaffected by linkage but the residual variance about this line is no longer constant but increases away from the mean.

Type
Short Paper
Information
Genetics Research , Volume 28 , Issue 2 , October 1976 , pp. 199 - 203
Copyright
Copyright © Cambridge University Press 1976

References

REFERENCES

Bulmer, M. G. (1971). The effect of selection on genetic variability. American Naturalist 105, 201–211.CrossRefGoogle Scholar