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Lethal interactions of the eye-gone and eyeless mutants in Drosophila melanogaster

Published online by Cambridge University Press:  14 April 2009

David M. Hunt
David M. Hunt
Affiliation:
M.R.C. Experimental Genetics Unit, Department of Animal Genetics, University College London, Wolfson House, 4 Stephenson Way, London, N.W.1

Summary

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A synthetic lethal system involving homozygous combination of the non-allelic eye mutants eye-gone and eyeless is described. The major lethal crisis is towards the end of the pupal instar although a number of double homozygotes die at pupation. The pupal lethal crisis can be overcome in a number of individuals by the experimental removal of the operculum from differentiated pupae. However, only a few of the resulting enclosed double homozygotes proved fully viable, the remainder dying almost immediately after emergence. Dissection of the surviving adults revealed that the brain is located in the anterior thorax.

Type
Research Article
Information
Genetics Research , Volume 15 , Issue 1 , February 1970 , pp. 29 - 34
Copyright
Copyright © Cambridge University Press 1970

References

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