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Genomic imprinting: normal complementation of murine chromosome 16

  • Christoph N. Berger (a1) and Charles J. Epstein (a1) (a2)

Summary

Parental imprinting effects for chromosome 16 were investigated using disomic animals which were obtained by mating (Rb32Lub × Rb2H) F1 mice. Two allelic forms of the enzyme CuZn-superoxide dismutase, Sod-1a and Sod-1c, were` used to identify maternally or paternally disomic animals. Both types of disomic animals were found with the expected frequencies and did not visibly differ from one another or from non-disomic animals. These results indicate that the genomic imprinting mechanism either does not act on chromosome 16, or, if it does, does not do so in a manner which affects normal development.

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References

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Genomic imprinting: normal complementation of murine chromosome 16

  • Christoph N. Berger (a1) and Charles J. Epstein (a1) (a2)

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