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Genetical and embryological comparison of two mutations which cause foetal blebs in mice

Published online by Cambridge University Press:  14 April 2009

Elizabeth M. Center
Elizabeth M. Center
Affiliation:
Department of Biological Sciences, Stanford University, Stanford, CA 94305

Summary

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Mutants with abnormalities which were the consequence of the formation of haematomas during gestation were designated as ‘foetal haematomata’ (fh). The fh homozygotes were found to be morphologically and embryologically very similar to myelencephalic bleb (my) mice. It was also found, however, that the fh and my mutants were separate genetic entities due to two independently segregating recessive genes.

Type
Research Article
Information
Genetics Research , Volume 29 , Issue 2 , April 1977 , pp. 147 - 157
Copyright
Copyright © Cambridge University Press 1977

References

REFERENCES

Beasley, A. B. & Crutchfield, F. L. (1969). Development of a mutant with abnormalities of the eye and extremities. Anatomical Record 63, 293 (Abstract).Google Scholar
Burdi, A. R. (1965). Toluidine blue-alizarin red S staining of cartilage and bone in wholemount skeletons in vitro. Stain Technology 40, 45–48.CrossRefGoogle ScholarPubMed
Carter, T. C. (1959). Embryology of the Little & Bagg X-rayed mouse stock. Journal of Genetics 56, 401–435.CrossRefGoogle Scholar
Center, E. M. (1971). Genetics and embryology of the fh (fetal hematomata) anomalies in the mouse. Genetics 68, S 9 (Abstract).Google Scholar
Center, E. M., Hunter, R. L. & Dodge, A. H. (1967). Effects of the luxoid gene (lu) on liver esterase isozymes of the mouse. Genetics 55, 349–358.CrossRefGoogle Scholar
Green, M. C. (1952). A rapid method for clearing and staining specimens for the demonstration of bone. Ohio Journal of Science 52, 31–33.Google Scholar
Green, M. L. (1955). Luxoid – A new heredity leg and foot abnormality in the house mouse. Journal of Heredity 46, 90–100.CrossRefGoogle Scholar
Grüneberg, H. (1943). The development of some external features in mouse embryos. Journal of Heredity 34, 88–92.CrossRefGoogle Scholar
Grüneberg, H. (1952). The Genetics of the Mouse, 2nd ed.Martinus Nijhoff.Google Scholar
Grüneberg, H. (1963). The Pathology of Development. John Wiley.Google Scholar
Schiffman, M. B., Satorineaou, M. L., Lewis, S. E., Turchin, H. A., & Gluecksohn-Waelsch, S. (1975). Lipid deficiencies, leukocytosis, brittle skin – A lethal syndrome caused by a recessive mutation, edematous (oed) in the mouse. Genetics 81, 525–536.CrossRefGoogle ScholarPubMed