Hostname: page-component-77c89778f8-5wvtr Total loading time: 0 Render date: 2024-07-17T02:24:16.406Z Has data issue: false hasContentIssue false
  • English
  • Français

A genetic analysis of non-disjunction and mitotic recombination in Neurospora crassa

Published online by Cambridge University Press:  14 April 2009

S. F. H. Threlkeld  and
J. M. Stoltz
S. F. H. Threlkeld
Affiliation:
Department of Biology, McMaster University, Hamilton, Ontario, Canada
J. M. Stoltz
Affiliation:
Department of Biology, McMaster University, Hamilton, Ontario, Canada

Summary

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

The frequency of the more common patterns of non-disjunction in Neurospora was studied. Detection of these asci was accomplished by the use of pantothenate requiring strains grown on reduced amounts of pantothenate, so that combinations of dark, pale, and aborted spores provided evidence of non-disjunction. The isolates from five non-disjunction asci were examined in detail and an apparently high frequency of mitotic recombination was detected for presumed disomic isolates. An hypothesis concerning a mechanism of non-disjunction is presented.

Type
Research Article
Information
Genetics Research , Volume 16 , Issue 1 , August 1970 , pp. 29 - 35
Copyright
Copyright © Cambridge University Press 1970

References

REFERENCES

Coyle, M. B. & Pittenger, T. H. (1964). Somatic recombination from pseudowild types of Neurospora recovered from 4:4 asci. Genetics 50, 242–243.(abstr.).Google Scholar
Mitchell, M. B., Pittenger, T. H. & Mitchell, H. K. (1952). Pseudowild types in Neurospora crassa. Proceedings of the National Academy of Sciences, U.S.A. 38, 569–580.CrossRefGoogle ScholarPubMed
Pittenger, T. H. (1953). The general incidence of pseudowild types in Neurospora crassa. Genetics 39, 326–342.CrossRefGoogle Scholar
Pittenger, T. H. & Coyle, M. B. (1963). Somatic recombination in pseudowild type cultures of Neurospora crassa. Proceedings of the National Academy of Sciences, U.S.A. 49, 445–451.CrossRefGoogle ScholarPubMed
Stack, S. M. & Brown, W. V. (1969). Somatic pairing, reduction and recombination: an evolutionary hypothesis of meiosis. Nature, London, 222, 1275–1276.CrossRefGoogle ScholarPubMed
Threlkeld, S. F. H. (1962). Some asci with non-identical sister spores from a cross in Neurospora crassa. Genetics 47, 1187–1198.CrossRefGoogle Scholar
Threlkeld, S. F. H. (1965). Pantothenic acid requirements for spore colour in Neurospora crassa. Canadian Journal of Genetics and Cytology 7, 171–173.CrossRefGoogle ScholarPubMed
Threlkeld, S. F. H. & Stephens, V. (1966). Ascospore isolates of Neurospora crassa giving rise to cultures containing two or more genetically different nuclei. Canadian Journal of Genetics and Cytology, 8, 414–421.CrossRefGoogle Scholar
Vogel, H. J. (1956). A convenient growth medium for Neurospora (Medium N). Microbial Genetics Bulletin 13, 42–43.Google Scholar
Westergaard, M. (1964). Studies on the mechanisms of crossing-over. I. Theoretical considerations. Comptes rendus des Travaux du Laboratoire, Carlsberg 34, 359–405.Google ScholarPubMed