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The contribution of plasmid and host genes to plasmid-mediated interference with phage growth

Published online by Cambridge University Press:  14 April 2009

Victoria Hughes  and
G. G. Meynell
Victoria Hughes
Affiliation:
Biological Laboratory, University of Kent, Canterbury, Kent CT2 7NJ, England
G. G. Meynell
Affiliation:
Biological Laboratory, University of Kent, Canterbury, Kent CT2 7NJ, England

Summary

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The R factors, R56 and R64, interfere with the growth of several otherwise unrelated phages, including λ, P22 and T7. In addition, λvir is inhibited more strongly in λ lysogens carrying either R factor when the prophage has an intact O – P region. Interference does not occur in certain str A R+ hosts but may reappear if they also carry other mutations affecting ribosomal proteins. Host mutants not permitting interference were isolated but were not strA. Non-interfering plasmid mutants were also isolated, of which some also failed to cause interference after transfer to a different host genus.

Type
Research Article
Information
Genetics Research , Volume 30 , Issue 2 , October 1977 , pp. 179 - 185
Copyright
Copyright © Cambridge University Press 1977

References

REFERENCES

Bachmann, B. J. (1972). Pedigrees of some mutant strains of Escherichia coli K-12. Bacteriological Reviews 36, 525–557.CrossRefGoogle ScholarPubMed
Bannister, D. & Glover, S. W. (1968). Restriction and modification of bacteriophages by R+ strains of Escherichia coli K12. Biochemical and Biophysical Research Communications 30, 735–738.CrossRefGoogle Scholar
Blumberg, D. D., Mabie, C. T. & Malamy, M. H. (1976). T7 protein synthesis in F-factor-containing cells: evidence for an episomally induced impariment of translation and its relation to an alteration in membrane permeability. Journal of Virology 17, 94–105.CrossRefGoogle Scholar
Breckenridge, L. & Gorini, L. (1970). Genetic analysis of streptomycin resistance in Escherichia coli. Genetics 65, 9–25.CrossRefGoogle ScholarPubMed
Britton, J. R. & Haselkorn, R. (1975). Permeability lesions in male Escherichia coli infected with bacteriophage T7. Proceedings of the National Academy of Sciences, U.S.A. 72, 2222–2226.CrossRefGoogle ScholarPubMed
Chakrabarti, S. & Gorini, L. (1975 a). Growth of bacteriophages MS2 and T7 on streptomycin-resistant mutants of Escherichia coli. Journal of Bacteriology 121, 670–674.CrossRefGoogle ScholarPubMed
Chakrabarti, S. L. & Gorini, L. (1975 b). A link between streptomycin and rifampicin mutation. Proceedings of the National Academy of Sciences, U.S.A. 72, 2084–2087.CrossRefGoogle ScholarPubMed
Condit, R. (1976). Who killed T7? Nature 260, 287–288.CrossRefGoogle Scholar
Hardy, K. G., Harwood, C. R. & Meynell, G. G. (1974). Expression of colicin factor E2-P9. Molecular and General Genetics 131, 313–331.CrossRefGoogle ScholarPubMed
Hedges, R. W. (1972). Phenotypic characterization of fi− R factors determining the restriction and modification hspII specificity. Molecular and General Genetics 115, 225–233.CrossRefGoogle Scholar
Hull, R. & Moody, E. E. (1976). Isolation and genetic characterization of Escherichia coli K-12 mutations affecting bacteriophage T5 restriction by the ColIb plasmid. Journal of Bacteriology 127, 229–236.CrossRefGoogle Scholar
Hyman, R. W., Brunovskis, I. & Summers, W. C. (1974). A biochemical comparison of the related bacteriophages T7, ø1, øII, W31, H, and T3. Virology 57, 189–206.CrossRefGoogle Scholar
Lawn, A. M., Meynell, E., Meynell, G. G. & Datta, N. (1967). Sex pili and the classification of sex factors in the enterobacteriaceae. Nature 216, 343–346.CrossRefGoogle ScholarPubMed
Meynell, G. G. & Meynell, E. (1970). Theory and Practice in Experimental Bacteriology, 2nd ed.Cambridge University Press.Google Scholar
Moyer, R. W., Fu, A. S. & Szabo, C. (1972). Regulation of bacteriophage T5 development by Coll factors. Journal of Virology 9, 804–812.CrossRefGoogle Scholar
Morrison, T. G. & Malamy, M. H. (1971). T7 translational control mechanisms and their inhibition by F factors. Nature New Biology 231, 37–41.CrossRefGoogle Scholar
Ponta, H., Pon, C. L., Herrlich, P., Gualerzi, C., Hirsch-Kauffmann, M., Pfennig-Yeh, M., Rahmsdorf, H.-J. & Schweiger, M. (1975). European Journal of Biochemistry, 59, 261–270.CrossRefGoogle Scholar
Spratt, B. G., Rowbury, R. J. & Meynell, G. G. (1973). The plasmid of Salmonella typhimurium LT2. Molecular and General Genetics 121, 347–353.CrossRefGoogle ScholarPubMed
Williams, L. & Meynell, G. G. (1971). Female-specific phages and F-minus strains of Escherichia coli K12. Molecular and General Genetics 113, 222–227.CrossRefGoogle ScholarPubMed
Yamada, Y. & Nakada, D. (1975). F-factor-mediated restriction of bacteriophage T7: protein synthesis in cell-free systems from T7-infected Escherichia coli F− and F+ cells. Journal cf Virology 16, 1483–1491.CrossRefGoogle ScholarPubMed
Zinder, N. D. (1958). Lysogenization and superinfection immunity in Salmonella. Virology 5. 291–326.CrossRefGoogle ScholarPubMed