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Association of genetic polymorphisms with embryonic mortality in the chicken: II. The B blood-group system and the pure and crossbred progeny of two populations

Published online by Cambridge University Press:  14 April 2009

D. G. Gilmour  and
J. R. Morton
D. G. Gilmour
Affiliation:
Department of Psychiatry and Neurology, New York University School of Medicine, and School of Agriculture, University of Cambridge, England
J. R. Morton
Affiliation:
Department of Psychiatry and Neurology, New York University School of Medicine, and School of Agriculture, University of Cambridge, England
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We have studied the association of the ten possible B blood-group genotypes with mortality during incubation in the 1966 generation of two relatively noninbred populations of Light Sussex chickens. These were related substrains 6D and 6F derived in the 1964 generation by equal division of strain 6, which we had previously studied in its 1962 generation. The B blood-group genotypes of zygotes but not of dams were associated with marked mortality differences in 6F, while in 6D almost no differences were found. Comparisons of the findings in 6D and 6F with the results previously published for the ancestor strain 6, after adjustment for overall between-population differences, showed marked changes between 6 and 6F in the mortalities associated with the five most frequent genotypes. In four of these, the mortalities in 6D were about half way between those in 6 and 6F. Taken together, these results provide evidence that the selective pressures on the B locus from differential embryonic mortality vary from generation to generation and even between populations differing apparently only slightly in environment and genetic composition.

In progeny of crosses between females from 6D and 6F with males from 5D and 5F respectively, the latter being two related Rhode Island Red/New Hampshire substrains, embryonic mortality was much lower than in the pure matings within 6D and 6F, and only a few associations with B blood-group genotypes of zygotes were found.

The results are discussed in relation to the general lack of association of polyallelic polymorphisms with aspects of fitness reported by other workers; and the importance is stressed of studying associations of genotypes rather than genes or serological factors.

Type
Research Article
Information
Genetics Research , Volume 15 , Issue 3 , June 1970 , pp. 265 - 284
Copyright
Copyright © Cambridge University Press 1970

References

REFERENCES

Allen, C. P. & Gilmour, D. G. (1962). The B blood group system of chickens. III. The effects of two heterozygous genotypes on the survival and egg production of multiple crosses. Genetics. Princeton 47, 1711–1718.CrossRefGoogle Scholar
Balaam, L. N. (1963). Multiple Comparisons—a sampling experiment. Australian Journal of Statistics 5, 62–84.CrossRefGoogle Scholar
Briles, W. E. & Allen, C. P. (1961). The B blood group system of chickens. II. The effects of genotype on livability and egg production in seven commercial inbred lines. Genetics. Princeton 46, 1273–1293.Google Scholar
Cochran, W. G. (1943). Analysis of variance for percentages based on unequal numbers. Journal of the American Statistical Association 38, 287–301.CrossRefGoogle Scholar
Duncan, D. B. (1955). Multiple range and multiple F tests. Biometrics 11, 1–42.Google Scholar
Duncan, D. B. (1957). Multiple range tests for correlated and heteroscedastic means. Biometrics 13, 164–176.CrossRefGoogle Scholar
Gilmour, D. G. (1960). Blood groups in chickens. British Poultry Science 1, 75–100.CrossRefGoogle Scholar
Gilmour, D. G. (1962). Current status of blood groups in chickens. Annals of the New York Academy of Sciences 97, 166–172.CrossRefGoogle Scholar
Haldane, J. B. S. & Jayakar, S. D. (1963). Polymorphism due to selection of varying direction. Journal of Genetics 58, 237–242.CrossRefGoogle Scholar
Harter, H. L. (1960). Critical values for Duncan's new multiple range test. Biometrics 16, 671–685.CrossRefGoogle Scholar
Kramer, C. Y. (1956). Extension of multiple range tests to group means with unequal numbers of replications. Biometrics 12, 307–310.CrossRefGoogle Scholar
Kramer, C. Y. (1957). Extension of multiple range tests to group correlated adjusted means. Biometrics 13, 13–18.CrossRefGoogle Scholar
Lush, I. E. (1961). Genetic polymorphisms in the egg albumen proteins of the domestic fowl. Nature, London 189, 981–984.CrossRefGoogle ScholarPubMed
Lush, I. E. (1964). Egg albumen polymorphisms in the fowl: loci II and III. Genetical Research 5, 39–49.CrossRefGoogle Scholar
Mandel, S. P. H. (1959). The stability of a multiple allelic system. Heredity. London 13, 289–302.CrossRefGoogle Scholar
Mather, K. (1949). Biometrical Genetics. London: Methuen.Google Scholar
Morton, J. R., Gilmour, D. G., McDermid, E. M. & Ogden, A. L. (1965). Association of blood-group and protein polymorphisms with embryonic mortality in the chicken. Genetics. Princeton 51, 97–107.CrossRefGoogle ScholarPubMed
Morton, N. E., Krieger, H. & Mi, M. P. (1966). Natural selection on polymorphisms in Northeastern Brazil. American Journal of Human Genetics 18, 153–171.Google ScholarPubMed
Neimann-Sørensen, A. & Robertson, A. (1961). The association between blood groups and several production characteristics in three Danish cattle breeds. Acta agriculturae Scandinavica. 11, 163–196.CrossRefGoogle Scholar
Ogden, A. L., Morton, J. R., Gilmour, D. G. & McDermid, E. M. (1962). Inherited variants in the transferrins and conalbumins of the chicken. Nature, London 195, 1026–1028.CrossRefGoogle ScholarPubMed
Stansfield, W. D., Bradford, G. E., Stormont, C. & Blackwell, R. L. (1964). Blood groups and their associations with production and reproduction in sheep. Genetics. Princeton 50, 1357–1367.CrossRefGoogle ScholarPubMed
Winer, B. J. (1962). Statistical Principles in Experimental Design. New York: McGraw-Hill.CrossRefGoogle Scholar