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An approach to the problem of whether clustering of functionally related genes occurs in higher organisms*

Published online by Cambridge University Press:  14 April 2009

R. C. Elston
Affiliation:
Departments of Biostatistics and Biochemistry, and the Genetics Curriculum, University of North Carolina at Chapel Hill, U.S.A.
Edward Glassman
Affiliation:
Departments of Biostatistics and Biochemistry, and the Genetics Curriculum, University of North Carolina at Chapel Hill, U.S.A.

Extract

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A Statistical analysis of the genome of D. melanogaster indicates that functionally related genes tend to be found on a particular chromosome and, when their locations within a given chromosome are measured in terms of map units, show a tendency to cluster; this clustering within chromosomes, however, is completely accounted for by the known clustering of all genes within chromosomes. Thus the analysis does not reveal any obvious functional significance for the arrangement of the genes within the chromosomes of this organism.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1967

References

REFERENCES

Braver, Norma B. (1956). The mutants of Drosophila melanogaster Classified According to Body Parts Affected. Carnegie Institution of Washington Publication 552A, Washington, D.C.Google Scholar
Bridges, Calvin B. & Brehme, Katherine S. (1944). The Mutants of Drosophila melanogaster. Carnegie Institution of Washington Publication 552, Washington, D.C.Google Scholar