Skip to main content Accessibility help
×
Home

Use of sevoflurane during cardiopulmonary bypass decreases incidence of awareness

  • B. Celebioğlu (a1), A. G. Pamuk (a1), Ü. Aypar (a1) and I. Paşaoğlu (a2)

Abstract

Background and objective: The role of sevoflurane has not been studied in relation to awareness during anaesthesia. We observed the effect of sevoflurane on the incidence of awareness during cardiopulmonary bypass for open-heart surgery.

Methods: Fifty-nine patients of age >17 yr undergoing open-heart surgery with cardiopulmonary bypass were randomly assigned to two groups. In both groups, induction was with etomidate, dehydrobenzperidol and fentanyl; anaesthesia was maintained with sevoflurane, fentanyl and N2O; vecuronium was used for muscular paralysis. Group 1 (30 patients) received dehydrobenzperidol and fentanyl during cardiopulmonary bypass; Group 2 (29 patients) received sevoflurane and fentanyl. Patients were given different auditory inputs during different phases of surgery. All patients were interviewed with standard questions 8 and 24h postoperatively for evidence of explicit awareness.

Results: Five patients in the dehydrobenzperidol group gave a history of awareness (16.67%) as opposed to none in the sevoflurane group. The difference in the incidences of awareness was significant (P < 0.05), but no differences were found between the interviews conducted at 8 and 24h. Sevoflurane and opioid combination reduced the incidence of awareness in open-heart surgery.

Copyright

Corresponding author

Correspondence to: Bilge Celebioğlu, Sehit Cetin Gorgu sokak 12/4, Maltepe 06570, Ankara, Turkey. E-mail: bilgesel@superonline.com.tr; Tel: +90 312 229 61 56; Fax: +90 312 310 96 00

Keywords

Use of sevoflurane during cardiopulmonary bypass decreases incidence of awareness

  • B. Celebioğlu (a1), A. G. Pamuk (a1), Ü. Aypar (a1) and I. Paşaoğlu (a2)

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed