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Post-tetanic burst count and train-of-four during recovery from vecuronium-induced intense neuromuscular block under different types of anaesthesia

Published online by Cambridge University Press:  16 August 2006

Y. Saitoh
Affiliation:
Department of Anesthesiology, Toride Kyodo General Hospital, Ibaraki
H. Tanaka
Affiliation:
Department of Anesthesiology, Toride Kyodo General Hospital, Ibaraki
Y. Fujii
Affiliation:
Department of Anesthesiology, Institute of Clinical Medicine, University of Tsukuba, Ibaraki
K. Makita
Affiliation:
Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
K. Amaha
Affiliation:
Department of Anesthesiology and Critical Care Medicine, Faculty of Medicine, Tokyo Medical and Dental University, Tokyo, Japan
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Abstract

Recovery of neuromuscular blockade after vecuronium 0.2 mg kg−1 was measured by post-tetanic burst count (PTBC) and train-of-four (TOF) in 120 adult patients anaesthetized by one of four techniques: neuroleptanaesthesia or one minimum alveolar concentration of isoflurane, enflurane, or sevoflurane. Onset of recovery was taken when there was reflex movement in response to carinal stimulation. The time course of recovery measured by burst count was similar for all four types of anaesthesia. Recovery of each of the twitches of the TOF was significantly shorter under neuroleptanaesthesia than under isoflurane, enflurane, or sevoflurane anaesthesia [times to return of T1 were 41.4±5.4, 51.5±10.6, 52.2±10.0, or 55.3±11.2 min (mean±SD). P<0.05]. The burst count at the onset of reflex movement was less under neuroleptanaesthesia than under isoflurane, enflurane, or sevoflurane anaesthesia (16.3±4.8, 26.7±6.7, 27.7±6.8, 28.0±8.4, P<0.05). The ratio of first twitch to control twitch at the onset of reflex movement was the same for all four types of anaesthesia.

Type
Original Article
Copyright
1998 European Society of Anaesthesiology

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