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Outcome for cardiothoracic surgical patients requiring multidisciplinary intensive care

Published online by Cambridge University Press:  11 July 2005

R. J. Roche
Affiliation:
John Radcliffe Hospital, Intensive Care Unit, Headington, Oxford, UK
A. D. Farmery
Affiliation:
John Radcliffe Hospital, Intensive Care Unit, Headington, Oxford, UK
C. S. Garrard
Affiliation:
John Radcliffe Hospital, Intensive Care Unit, Headington, Oxford, UK
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Summary

Background and objective: Patients who require multidisciplinary intensive care after cardiac surgery have a poor prognosis. The aim was to investigate factors in the mortality of this group of patients at 6 months.

Methods: A retrospective analysis was made of the 6-month mortality rate in 301 adults who required admission to a multidisciplinary intensive care unit following cardiac surgery from 1991 to 1997. Mortality was correlated with clinical and patient characteristic variables.

Results: The intensive care mortality rate was 34% and at 6 months after patients' discharge from intensive care it was 51%. There were positive correlations with death at 6 months for ventricular failure (odds ratio of death 3.4, P = 0.002), sepsis (odds ratio 3.0, P = 0.004) and age over 80 yr (odds ratio of death 9.2, P = 0.034). Patients who had undergone isolated coronary artery graft surgery (odds ratio of death 0.28, P = 0.036) or thoracic surgery (odds ratio of death 0.22, P = 0.042) had better 6-month outcomes. Patients with respiratory or renal failure in the absence of ventricular failure or sepsis had a 6-month mortality rate of 36%; but the lower mortality rate did not achieve statistical significance.

Conclusions: The 6-month mortality rate of 51% in a group of patients requiring multidisciplinary intensive care after cardiac surgery is consistent with previous studies; mortality was particularly high in extreme old age and in patients referred with sepsis or ventricular failure. Those patients with uncomplicated respiratory or renal failure had a better outcome than the group as a whole.

Type
Original Article
Copyright
© 2003 European Society of Anaesthesiology

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References

Favaloro R. Saphenous vein autograft replacement of severe segmental coronary artery occlusions: operative technique. Ann Thorac Surg 1968; 5: 334339.Google Scholar
Yusuf S, Zucker D, Peduzzi P, et al. Effect of coronary artery bypass surgery on survival: overview of 10-year results from randomised trials by the Coronary Artery Bypass Graft Surgery Trialists Collaboration. Lancet 1994; 344: 563570.Google Scholar
Westaby S, Pillai R, Parry A, et al. Does modern cardiac surgery require conventional intensive care? Eur J Cardiothorac Surg 1993; 7: 313318.Google Scholar
Reyes A, Vega G, Blancas R, et al. Early vs conventional extubation after cardiac surgery with cardiopulmonary bypass. Chest 1997; 112: 193201.Google Scholar
Chong JL, Pillai R, Fisher A, Grebenik C, Sinclair M, Westaby S. Cardiac surgery: moving away from intensive care. Br Heart J 1992; 68: 430433.Google Scholar
Cheng DC, Karski J, Peniston C, et al. Morbidity outcome in early versus conventional tracheal extubation after coronary artery bypass grafting: a prospective randomized controlled trial. J Thorac Cardiovasc Surg 1996; 112: 755764.Google Scholar
Bashour CA, Yared JP, Ryan TA, et al. Long-term survival and functional capacity in cardiac surgery patients after prolonged intensive care. Crit Care Med 2000; 28: 38473853.Google Scholar
Thompson M, Elton R, Mankad P, et al. Prediction of requirement for, and outcome of, prolonged mechanical ventilation following cardiac surgery. Cardiovasc Surg 1997; 5: 376381.Google Scholar
Trouillet JL, Scheimberg A, Vuagnat A, Fagon JY, Chastre J, Gibert C. Long term outcome and quality of life of patients requiring multidisciplinary intensive care unit admission after cardiac operations. J Thorac Cardiovasc Surg 1996; 112: 926934.Google Scholar
Kollef MH, Wragge T, Pasque C. Determinants of mortality and multiorgan dysfunction in cardiac surgery patients requiring prolonged mechanical ventilation. Chest 1995; 107: 13951401.Google Scholar
Holmes L, Loughead K, Treasure T, Gallivan S. Which patients will not benefit from further intensive care after cardiac surgery? Lancet 1994; 344: 12001202.Google Scholar
Ryan TA, Rady MY, Bashour CA, Leventhal M, Lytle B, Starr NJ. Predictors of outcome in cardiac surgical patients with prolonged intensive care stay. Chest 1997; 112: 10351042.Google Scholar
Bone RC, Balk RA, Cerra FB, et al. Definitions for sepsis and organ failure and guidelines for the use of innovative therapies in sepsis. The ACCP/SCCM Consensus Conference Committee. Chest 1992; 101: 16441655.Google Scholar
Altman DG. Practical Statistics for Medical Research. New York, USA: Chapman & Hall, 1991.
Gehlot AS, Santamaria JD, White AL, Ford GC, Ervine KL, Wilson AC. Current status of coronary artery grafting in patients 70 years of age and older. Aust N Z J Surg 1995; 65: 177181.Google Scholar
Deiwick M, Tandler R, Mollhoff T, et al. Heart surgery in patients aged eighty and above: determinants of mortality and morbidity. Thorac Cardiovasc Surg 1997; 45: 119126.Google Scholar
Geraci JM, Rosen AK, Ash AS, McNiff KJ, Moskowitz MA. Predicting the occurrence of adverse events after coronary artery bypass surgery. Ann Intern Med 1993; 118: 1824.Google Scholar
Hammermeister KE, Burchfiel C, Johnson R, Grover FL. Identification of patients at greatest risk for developing major complications at cardiac surgery. Circulation 1990; 82 (Suppl IV): 380389.Google Scholar
Chang RW, Jacobs S, Lee B, Pace N. Predicting deaths among intensive care unit patients. Crit Care Med 1988; 16: 3442.Google Scholar
Higgins T, Starr N, Lee J-C, Beck G, Estafanous F. Predicting prolonged intensive care unit length of stay following coronary artery bypass surgery. Clin Intensive Care 1999; 10: 175182.Google Scholar
Rady MY, Ryan T. Perioperative predictors of extubation failure and the effect on clinical outcome after cardiac surgery. Crit Care Med 1999; 27: 340347.Google Scholar
Söderlind K, Rutberg H, Olin C. Late outcome and quality of life after complicated heart operations. Ann Thorac Surg 1997; 63: 124128.Google Scholar
Nielsen D, Sellgren J, Ricksten SE. Quality of life after cardiac surgery complicated by multiple organ failure. Crit Care Med 1997; 25: 5257.Google Scholar