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Virological and epidemiological studies on an outbreak of aseptic meningitis caused by echovirus 4 in northern Japan in 1964*

Published online by Cambridge University Press:  15 May 2009

Yorio Hinuma ,
Katsumi Uruno ,
Morihiro Morita ,
Nakao Ishida  and
Tooru Nakao
Yorio Hinuma
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Katsumi Uruno
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Morihiro Morita
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Nakao Ishida
Affiliation:
Department of Bacteriology, Tohoku University School of Medicine, Sendai, Japan
Tooru Nakao
Affiliation:
Pediatric Clinic, Aomori Prefectural Central Hospital, Aomori, Japan
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During the summer and autumn of 1964, echovirus 4 was found widely distributed in northern Japan; this virus was associated with localized outbreaks of iaseptic meningitis in many regions. The evidence that the echovirus was aetio-logically related to aseptic meningitis was shown by the virus isolation from cerebrospinal fluids and faeces and the serodiagnosis of paired sera in many patients: Age-specific sero-immunity and morbidity rate suggested that echovirus 4 had spread extensively in about 1954. The strains of echovirus 4 isolated in the 1964; epidemic were similar to the prototype strain, Pesascek, in biological characteristics.

Type
Research Article
Information
Journal of Hygiene , Volume 64 , Issue 1 , March 1966 , pp. 53 - 64
Copyright
Copyright © Cambridge University Press 1966

References

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