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Suppurative Cholecystitis with Cholelithiasis in a Human “Carrier” of the Bacillus enteritidis of Gaertner

Published online by Cambridge University Press:  15 May 2009

George Dean
Affiliation:
Professor of Pathology, Aberdeen University
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In a case of suppurative cholecystitis with cholelithiasis a bacillus was isolated from the pus, gall bladder, and stools which has the morphological, biological and cultural characters of B. enteritidis Gaertner. This bacillus is pathogenic for the rat, rabbit and guinea-pig, and gives rise to the characteristic lesions produced by the Gaertner bacillus. The serum of the patient agglutinated the three strains of bacilli isolated from the above mentioned sources and the original Gaertner strain in a dilution of 1 in 40. A serum, prepared by injecting B. enteritidis Gaertner (original strain) into a rabbit, agglutinated the three strains isolated from the case and the homologous bacillus in almost the same dilutions.

A serum prepared from any of the three bacilli agglutinates the homologous organism, the other two strains and the original Gaertner bacillus in almost the same titre. The sera homologous to allied organisms do not agglutinate these bacilli. Absorption tests confirm these results and prove that the bacilli isolated are identical with the Gaertner bacillus.

The chief points of interest in the case are that:

1. It forms a link in the chain of evidence showing that as in the case of the paratyphoid bacillus the B. enteritidis Gaertner may give rise, not only to the more acute toxic from of poisoning, but also to a sub-acute paratyphoid type of the disease.

2. It establishes the association of B. enteritidis Gaertner with suppurative cholecystitis and with cholelithiasis.

3. It proves that this bacillus may have its habitat in the gall bladder and be shed out at intervals into the faeces, in a manner exactly analogous to what occurs in the case of typhoid and paratyphiod infections.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1911

References

Aschoff, L. and Bacmeister, A. (1909). Die Cholelithiasis. Fisher. Jena, 1909.Google Scholar
Aumann, (1911). Über Befunde von Bakterien der Paratyphusgruppe mit besonderer Berücksichtigung der Ubiquitätsfrage. Centralbl. f. Bakteriol. etc., Abt. I., Originale lvii. 310.Google Scholar
Bainbridge, F. A. (1909). On the paratyphoid and “food-poisoning” bacilli and on the nature and efficiency of certain rat viruses. Journ. of Pathol. and Bacteriol., xiii. 443.CrossRefGoogle Scholar
Bainbridge, and Dudfield, (1911). An outbreak of acute gastro-enteritis caused by B. paratyphosus B. Journ. of Hygiene, xi. 24.CrossRefGoogle Scholar
Chiarolanza, R. (1908). Experimentelle Untersuchungen über die Beziehungen der Typhusbazillen zu der Gallenblase und den Gallénwegen. Zeitschr. f. Hygiene, lxii. 11.Google Scholar
Cushing, H. (1899). Observations upon the origin of gall bladder infections and upon the experimental formation of gall stones Johns Hopkins Hosp. Bull x. 166. (Contains older literature.)Google Scholar
Doerr, (1905). Experimentelle Untersuchungen über das Fortwuchern von Typhusbazillen in der Gallenblase. Centralbl. f. Bakteriol. Abt. I. Orig. xxxix. 624.Google Scholar
Dudgeon, L. S.. (1908). On the latent persistence and the reactivation of pathogenic bacteria in the body. Lancet, p. 1651.Google Scholar
Evers, and Mühlens, (1909). Cholelithiasis Paratyphosa und Paratyphuserkrankung ein Beitrag zur Frage der Bazillenträger. Deutsche militar-ärztl. Zeitschr., xxxviii. 366.Google Scholar
Forster, J. (1908). Über die Beziehungen des Typhus und Paratyphus zu den Gallenwegen. München. med. Wochenschr., p. 1.Google Scholar
Forster, J., and Kayser, H.. (1905). Über das Vorkommen von Typhusbazillen in der Galle von Typhuskranken und Typhusbazillen-trägern. München. med. Wochenschr., p. 1473.Google Scholar
Gaehtgens, (1907). Über die Bedeutung des Vorkommens der Paratyphusbazillen (Typhus B). Arb. a. d. Kaiserl. Gesundheitsamte, xxv. 203.Google Scholar
Gilbert, et Lippmann, (1907). Contribution à P'étude bactériologique des calculs biliaires. Rôle des microbes anaérobies. Compt. Rend. Soc. de Biol., ii. 405.Google Scholar
Hamilton, A. (1910). The value of Opsonic Determination in the discovery of Typhoid carriers. Journ. Infect. Diseases, vii. 393.CrossRefGoogle Scholar
Hilgermann, R.. (1909). Bericht über das erste Jahr der Tätigkeit des Medizinal untersuchungsamtes der Königl. Regierung zu Coblenz. Klin. Jahrb., xx. 103128.Google Scholar
Hilgermann, R. (1910). Über Paratyphus B. Klin. Jahrb., xxiv. 338.Google Scholar
Koch, J. (1908). Typhusbazillen und Gallenblase. Zeitschr. f. Hygiene, lxii. 1.Google Scholar
Laubenheimer, K. (1908). Zur Ätiologie der Cholecystitis. Zeitschr. f. Hygiene, liii. 64.CrossRefGoogle Scholar
Ledingham, J. C. G. (1910). Report to the Local Government Board on the Enteric Fever “Carrier”; being a review of current knowledge on this subject.Google Scholar
Mayer, O. (1909). Über die Bewertung des Befundes von Paratyphus-B-Bazillen in menschlichen Darmentleerungen bei akuter Gastroenteritis ohne Gruber-Widalsche Reaktion. Klin. Jahrb., xxi. 325.Google Scholar
Zweifel, E. (1911). Bakteriologische Untersuchungen von rohem Hackfleisch, mit besonderer Berücksichtigung des Bacillen der Paratyphusgruppe. Centralbl. f. Bakteriologie, 1 Abt., Orig. lviii, Heft 2.Google Scholar