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Suggestions for a New Criterion of a Positive Wassermann Reaction based on an Analysis of 2334 Quantitative Tests1

Published online by Cambridge University Press:  15 May 2009

C. H. Browning
Affiliation:
From the Bland-Sutton Institute, Middlesex Hospital and the Pathological Department of the University and Western Infirmary, Glasgow.
E. L. Kennaway
Affiliation:
From the Bland-Sutton Institute, Middlesex Hospital and the Pathological Department of the University and Western Infirmary, Glasgow.
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Examination of the records of a large number of quantitative Wassermann tests has suggested a new and simple criterion of a positive reaction. This is based upon a comparison of the amounts of complement giving complete lysis with any given serum, and with the negative control, respectively. Reasons are given for regarding this criterion as more satisfactory than that in common use. Details are given of the methods employed for the selection of a negative control serum, the estimation of degrees of lysis, and the provision of a suitable range of amounts of complement.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1920

References

Boas, (1914). Die Wassermannsche Reaktion. Berlin.Google Scholar
Browning, , Cruickshank, and Mackenzie, (1910). Journ. of Path. and Bact. XIV. 484.Google Scholar
Browning, , Cruickshank, and Kennaway, (1919). Lancet, I. 785.CrossRefGoogle Scholar
Browning, , Cruickshank, and Mackenzie, (1909). Zeitschr. f. Immunitätsforsch. II. 459.Google Scholar
Browning, , Cruickshank, (1911). Recent Advances in the Diagnosis and Treatment of Syphilis. London.Google Scholar
Fildes, and McIntosh, (1913). Brain, XXXVI. 193.CrossRefGoogle Scholar
Fildes, and McIntosh, (1913). Medical Research Committee, Special Report Series, No. 14.Google Scholar
Kennaway, and Wright, (1919). Journ. of Hygiene, XVIII. 255.CrossRefGoogle Scholar
Wassermann, (1913). See Wassermann and Lange. Handbuch d. Pathogen. Mikro-organismen (Kolle-Wassermann), 2 Ed. Berlin, VII. 951.Google Scholar