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The Specific Toxigenic Properties of Haemolytic Streptococci from Scarlatina and other Sources

Published online by Cambridge University Press:  15 May 2009

D. G. S. McLachlan
D. G. S. McLachlan
Affiliation:
From the Bacteriology Department, University of Edinburgh.
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1. Without exception, ninety-eight strains of haemolytic streptococci isolated from scarlet fever cases have been found to produce a toxic principle which in high dilutions is capable of evoking a cutaneous reaction in sus ceptible persons.

2. A certain proportion of haemolytic streptococci from other sources possess a similar toxigenic property. In the majority of such cases this property is only weakly developed as judged by quantitative tests. In a few instances a “toxin” is produced which is equally active with that of scarlatina strains.

3. Certain non-scarlatina strains produce “toxins” which evoke a cutane ous reaction both in known positive reactors and also in persons who do not react to a standard toxin from a scarlatina strain.

4. In the majority of cases the toxins produced by scarlatina strains are neutralised by the scarlatina antitoxic sera at present being used for therapeutic purposes, but a certain proportion of such toxins are not in the neutralised

5. The “toxins”produced by non-scaralation strains are in the majority of cases neutralised by the antitoxic sera.

Type
Research Article
Information
Journal of Hygiene , Volume 26 , Issue 1 , March 1927 , pp. 84 - 97
Copyright
Copyright © Cambridge University Press 1927

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