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Serotype-related enterotoxigenicity in Escherichia coli O6.H16 and O148.H28

Published online by Cambridge University Press:  15 May 2009

Sylvia M. Scotland ,
Roger J. Gross  and
Bernard Rowe
Sylvia M. Scotland
Affiliation:
Salmonella and Shigella Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
Roger J. Gross
Affiliation:
Salmonella and Shigella Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
Bernard Rowe
Affiliation:
Salmonella and Shigella Reference Laboratory, Central Public Health Laboratory, Colindale Avenue, London NW9 5HT
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Summary

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The ability of certain Escherichia coli strains to produce enterotoxin is determined by transmissible plasmids. It is therefore possible that any E. coli strain might be able to acquire such a plasmid and that the correlation between enterotoxigenicity and serotype might be random. However, recent studies show that the enterotoxigenic strains so far described belong to a restricted range of serotypes. Enterotoxigenic strains of E. coli O6.H16 and E. coli O148.H28 have been associated with outbreaks of diarrhoea in several countries, therefore strains of E. coli belonging to these serotypes were selected for further study.

Twenty-three strains of E. coli O6.H16 and 14 strains of E. coli O148.H28 were examined; 20 strains of E. coli O6.H16 and all 14 strains of E. coli 0148.H28 were enterotoxigenic but strains of E. coli O6 with flagellar antigens other than H16 and strains of E. coli O148 with flagellar antigens other than H28 were not enterotoxigenic. The examination of single colony subcultures derived from the E. coli O6.H16 strains showed that in some strains loss of enterotoxigenicity had occurred in a proportion of colonies.

Type
Research Article
Information
Journal of Hygiene , Volume 79 , Issue 3 , December 1977 , pp. 395 - 403
Copyright
Copyright © Cambridge University Press 1977

References

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