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Rubella-specific IgM reactivity in sera from cases of infectious mononucleosis

  • P. Morgan-Capner (a1), R. S. Tedder (a2) and J. E. Mace (a2)

Summary

Eight sera from 125 cases of infectious mononucleosis (IM) were reactive for rubella-specific IgM in an M-antibody capture radioimmunoassay. The reactivity of individual sera varied depending upon the source of the rubella antigen used in the assay. One serum gave strongly positive results with some rubella haemagglutinating antigens but negative results with others and may have contained an IgM antibody which was capable of distinguishing between strains of rubella virus.

If the diagnosis of rubella is based solely on detection in solid-phase immunoassay of rubella-specific IgM, IM should be excluded.

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References

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Carter, R. L. (1966). Antibody formation in infectious mononucleosis, II. Other 19S antibodies and false-positive serology. British Journal of Haematology 12, 268275.
Cradock-Watson, J. E., Bourne, M. S. & Vandervelde, E. M. (1972). IgG, IgA and IgM responses in acute rubella determined by the immunofluorescent technique. Journal of Hygiene 70, 473485.
Epstein, M. A. & Achong, B. G. (1977). Pathogenesis of infectious mononucleosis. Lancet ii, 12701272.
Henle, G. & Henle, W. (1979). The Virus as the Etiologic Agent of Infectious Mononucleosis: The Epstein—Barr Virus. Berlin, Heidelberg, New York: Springer-Verlag.
Kurtz, J. B., Mortimer, P. P., Mortimer, P. R., Morgan-Capner, P., Shafi, M. S. & White, G. B. B. (1980). Rubella antibody measured by radial haemolysis. Characteristics and performance of a simple screening method for use in diagnostic laboratories. Journal of Hygiene 84, 213222.
Morgan-Capner, P., Davies, E. & Pattison, J. R. (1980). Rubella-specific IgM detection using Sephacryl S-300 gel filtration. Journal of Clinical Pathology 33, 10821085.
Mortimer, P. P., Tedder, R. S., Hambling, M. H., Shafi, M. S., Burkhardt, F. & Schilt, U. (1981). Antibody capture radioimmunoassay for anti-rubella IgM. Journal of Hygiene 86, 139153.
Pattison, J. R. & Dane, D. S. (1975). The detection of specific IgM antibodies following infection with rubella virus. Journal of Clinical Pathology 28, 377382.
Rott, R., Drzeniek, R., Saber, M. S. & Reichert, T. (1966). Blood group substances, Forssman and mononucleosis antigens in lipid-containing RNA viruses. Archiv für die Gesamte Virusforschung 19, 273288.
Tender, R. S., Yao, J. L. & Anderson, M. J. (1982). The production of monoclonal antibodies to rubella haemagglutinin and their use in antibody-capture assays for rubella-specific IgM. Journal of Hygiene 88, 335350.
Urquhart, G. E. D. & Carson, H. G. (1982). Laboratory policy for rubella screening. Lancet ii, 1226.

Rubella-specific IgM reactivity in sera from cases of infectious mononucleosis

  • P. Morgan-Capner (a1), R. S. Tedder (a2) and J. E. Mace (a2)

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