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The Recognition of Four Red Cell Antigen-Antibody Systems in the Rabbit

Published online by Cambridge University Press:  15 May 2009

D. H. Heard
D. H. Heard
Affiliation:
Department of Pathology, University of Cambridge
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Summary

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Four red cell antigen-antibody systems in the rabbit are described.

Three of these systems, Z, Y and W, appear to be inherited as an allelomorphic series. The fourth is inherited independently.

Some of the serological properties which allow these sera to be recognized are described and attention is drawn to a property of rabbit red cells, manifested by a variation in their susceptibility to agglutination by homologous antisera, which can complicate the separation of a mixture of antibodies in one serum.

Type
Research Article
Information
Journal of Hygiene , Volume 53 , Issue 4 , December 1955 , pp. 398 - 407
Copyright
Copyright © Cambridge University Press 1955

References

Castle, W. E. & Keeler, C. E. (1933). Blood group inheritance in the rabbit. Proc. Nat. Acad. Sci. 19, 92.Google Scholar
Coombs, R. R. A., Mourant, A. E. & Race, R. R. (1945). A new test for the detection of weak and 'incomplete' Eh agglutinins. Brit. J. exp. Path. 26, 255.Google Scholar
Coombs, R. R. A., Moueant, A. E. & Race, R. R. (1946). In vivo sensitization of red cells in babies with haemolytic disease. Lancet, i, 264.CrossRefGoogle Scholar
Diamond, K. & Denton, R. L. (1945). Rh agglutination in various media with particular reference to the value of albumin. J. Lab. din. Med. 31, 821.Google Scholar
Fischer, W. (1935). Ueber blutgruppeneigenschaften beim kaninchen. Z. Immumitdts-Forsch. 86, 97.Google Scholar
Heard, D. H. (1955). Factors influencing the agglutinability of red cells. Variation of the red cells of the rabbit in susceptibility to agglutination by homologous iso-antisera. J. Hyg., Camb., 53, 408.Google ScholarPubMed
Heard, D. H., Hinde, I. T. & Mynors, L. S. (1949). An experimental study of haemolytic disease of the newborn due to iso-immunization of pregnancy. An attempt to produce the syndrome in the rabbit. J. Hyg., Camb., 47, 119.Google Scholar
Keeler, C. E. & Castle, W. E. (1933). A further study of blood groups of the rabbit. Proc. Xat. Acad. Sci. 19, 403.Google Scholar
Keeler, C. E. & Castle, V. E. (1934 a). Blood group incompatability in rabbit embryos and in man. Proc. Nat. Acad. Sci. 20, 273.CrossRefGoogle ScholarPubMed
Keeler, C. E. & Castle, W. E. (1934 b). The influence of pregnancy upon the titre of immune (blood group) antibodies in the rabbit. Proc. Nat. Acad. Sci. 20, 465.Google Scholar
Kellner, A. & Hedal, E. F. (1953 a). Experimental erythroblastosis fetalis in rabbit. I. Characterization of a pair of allelic blood group factors and their specific immune isoantibodies. J. exp. Med. 97, 33.Google Scholar
Kellner, A. & Hedal, E. F. (1953 b). Experimental erythroblastosis fetalis in rabbits. II. The passage of blood group antigens and their specific iso-antibodies across the placenta. J. exp. Med. 97, 51.CrossRefGoogle Scholar
Kjstopfmacher, H. P. (1942). A study of four antigenic components of rabbit erythrocytes. J. Immunol. 44, 121.CrossRefGoogle Scholar
Levine, P. & Landsteiner, K. (1929). On immune iso-agglutinins in rabbits. J. Immunol. 17, 559.CrossRefGoogle Scholar
Levine, P. & Landsteiner, K. (1931). On immune iso-agglutinins in rabbits. Second paper. J. Immunol. 21, 513.CrossRefGoogle Scholar
Morton, J. A. & Pickles, M. M. (1947). Use of trypsin in the detection of incomplete anti-Ehantibodies. Nature, Lond., 159, 779.CrossRefGoogle Scholar
Robertson, O. H. & Rous, P. (1922). Sources of the antibodies developing after repeated transfusion. J. exp. Med. 35, 141.CrossRefGoogle ScholarPubMed