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Reactions of T Vi and Ballerup Vi haptenes with antisera against Vi-coated erythrocytes

Published online by Cambridge University Press:  15 May 2009

David Chi-Yen Chu  and
Robert K. Hoyt
David Chi-Yen Chu
Affiliation:
Department of Bacteriology and Serology, Division of Laboratories, Cedars of Lebanon Hospital, Los Angeles 29, California
Robert K. Hoyt
Affiliation:
Department of Bacteriology and Serology, Division of Laboratories, Cedars of Lebanon Hospital, Los Angeles 29, California
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1. T Vi-coated rabbit erythrocytes, when injected into rabbits, stimulate the production of a (pure) Vi antiserum.

2. The T Vi extract was found to be heat-stable with respect to antigenicity and agglutinability, as shown by means of coated erythrocytes.

3. By means of cross-absorption tests it was shown that the Vi antigen of S. typhi differs from the Vi antigen of the Ballerup organism.

4. The need for caution in relying on resistance to heat as a character of groups of antigens is emphasized.

We wish to thank Dr P. R. Edwards, of the Communicable Disease Centre, U.S.P.H.S., and Dr Alcor S. Browne, California State Department of Health, for supplying certain of the cultures and specimens of typing serum used in these studies.

Type
Research Article
Information
Journal of Hygiene , Volume 52 , Issue 1 , March 1954 , pp. 100 - 104
Copyright
Copyright © Cambridge University Press 1954

References

REFERENCES

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