Skip to main content Accessibility help
×
Home

Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study

  • Lauge Østergaard (a1), Kasper Adelborg (a2), Jens Sundbøll (a2), Lars Pedersen (a2), Emil Loldrup Fosbøl (a1) and Morten Schmidt (a2) (a3)...

Abstract

The positive predictive value of an infective endocarditis diagnosis is approximately 80% in the Danish National Patient Registry. However, since infective endocarditis is a heterogeneous disease implying long-term intravenous treatment, we hypothesiszed that the positive predictive value varies by length of hospital stay. A total of 100 patients with first-time infective endocarditis in the Danish National Patient Registry were identified from January 2010 – December 2012 at the University hospital of Aarhus and regional hospitals of Herning and Randers. Medical records were reviewed. We calculated the positive predictive value according to admission length, and separately for patients with a cardiac implantable electronic device and a prosthetic heart valve using the Wilson score method. Among the 92 medical records available for review, the majority of the patients had admission length ⩾2 weeks. The positive predictive value increased with length of admission. In patients with admission length <2 weeks the positive predictive value was 65% while it was 90% for admission length ⩾2 weeks. The positive predictive value was 81% for patients with a cardiac implantable electronic device and 87% for patients with a prosthetic valve. The positive predictive value of the infective endocarditis diagnosis in the Danish National Patient Registry is high for patients with admission length ⩾2 weeks. Using this algorithm, the Danish National Patient Registry provides a valid source for identifying infective endocarditis for research.

  • View HTML
    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study
      Available formats
      ×

Copyright

Corresponding author

Author for correspondence: Lauge Østergaard, E-mail: laugeoestergaard@gmail.com

References

Hide All
1.Delahaye, F et al. (2007) In-hospital mortality of infective endocarditis: prognostic factors and evolution over an 8-year period. Scandinavian Journal of Infectious Diseases 39, 849857.
2.Schmidt, M et al. (2015) The Danish National Patient Registry: a review of content, data quality, and research potential. Clinical Epidemiology 7, 449490.
3.Erichsen, P, Gislason, GH and Bruun, NE (2016) The increasing incidence of infective endocarditis in Denmark, 1994–2011. European Journal of Internal Medicine 35, 9599.
4.Tan, C et al. (2016) Accuracy of administrative data for identification of patients with infective endocarditis. International Journal of Cardiology 224, 162164.
5.Jolly, SS et al. (2015) Randomized trial of primary PCI with or without routine manual thrombectomy. New England Journal of Medicine 372, 13891398.
6.Programme | ISCVID Dublin 2017. Available at http://iscviddublin2017.com/programme/ (Accessed 5 November 2017).
7.Sundbøll, J et al. (2016) Positive predictive value of cardiovascular diagnoses in the Danish National Patient Registry: a validation study. BMJ Open 6, e012832.
8.Habib, G et al. (2015) 2015 ESC guidelines for the management of infective endocarditis: the task force for the management of infective endocarditis of the European Society of Cardiology (ESC)Endorsed by: European Association for Cardio-Thoracic Surgery (EACTS), the European Association of Nuclear Medicine (EANM). European Heart Journal 36, 30753128.
9.Henriksen, DP et al. (2015) Comparison of the five danish regions regarding demographic characteristics, healthcare utilization, and medication use – a descriptive cross-sectional study. Dalal K, ed. PLoS ONE 10, e0140197.
10.Wilson, EB (1927) Probable inference, the law of succession, and statistical inference. Journal of the American Statistical Association 22, 209.
11.Habib, G, Thuny, F and Avierinos, J-F (2008) Prosthetic valve endocarditis: current approach and therapeutic options. Progress in Cardiovascular Diseases 50, 274281.
12.Madsen, M (2003) The validity of the diagnosis of acute myocardial infarction in routine statistics. A comparison of mortality and hospital discharge data with the Danish MONICA registry. Journal of Clinical Epidemiology 56, 124130.
13.Wildenschild, C et al. (2014) Registration of acute stroke: validity in the Danish Stroke Registry and the Danish National Registry of Patients. Clinical Epidemiology 6, 2736.
14.Rix, TA et al. (2012) Validity of the diagnoses atrial fibrillation and atrial flutter in a Danish patient registry. Scandinavian Cardiovascular Journal: SCJ 46, 149153.

Keywords

Related content

Powered by UNSILO

Positive predictive value of infective endocarditis in the Danish National Patient Registry: a validation study

  • Lauge Østergaard (a1), Kasper Adelborg (a2), Jens Sundbøll (a2), Lars Pedersen (a2), Emil Loldrup Fosbøl (a1) and Morten Schmidt (a2) (a3)...

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed.