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Population dynamics of Staphylococcus aureus from Northeastern Nigeria in 2007 and 2012

  • K. O. OKON (a1), A. O. SHITTU (a2), A. A. KUDI (a3), H. UMAR (a4), K. BECKER (a5) and F. SCHAUMBURG (a5)...

Summary

The population structure of Staphylococcus aureus is changing globally but the situation regarding dominant clones in sub-Saharan Africa is not clear. We therefore assessed changes in the population structure of clinical S. aureus isolates obtained in 2007 (n = 75) and 2012 (n = 75) from Northeastern Nigeria. A reduction in resistance to penicillin, gentamicin, erythromycin and clindamycin was observed in 2012. A decrease of methicillin resistance rates (13·3% to 8·0%) was associated with the decline of the ST241 MRSA clone. The proportion of Panton–Valentine leukocidin (PVL)-positive isolates also decreased from 65·3% to 44%, and was linked with the emergence of PVL-negative ST601 clone in 2012. The significant decline in antibiotic resistance in the study area is in contrast to the worldwide trend of increasing resistance rates.

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Copyright

Corresponding author

*Author for correspondence: Dr F. Schaumburg, Institute of Medical Microbiology, University Hospital Münster, Domagkstr. 10, 48149 Münster, Germany. (Email: frieder.schaumburg@ukmuenster.de)

References

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