Hostname: page-component-84b7d79bbc-fnpn6 Total loading time: 0 Render date: 2024-07-27T23:45:29.401Z Has data issue: false hasContentIssue false
  • English
  • Français

Observations on a poliovirus variant

Published online by Cambridge University Press:  15 May 2009

F. J. Austin  and
J. A. R. Miles
F. J. Austin
Affiliation:
Department of Microbiology, University of Otago, New Zealand
J. A. R. Miles
Affiliation:
Department of Microbiology, University of Otago, New Zealand
Rights & Permissions [Opens in a new window]

Extract

Core share and HTML view are not available for this content. However, as you have access to this content, a full PDF is available via the ‘Save PDF’ action button.

1. Some of the biological and physical properties of one member (FES) of an inter-related group of viruses were examined and compared with the Saukett strain of poliovirus Type 3.

2. The accumulated data of particle size, immunological relationship, and host tissue and cell tropism indicates that this is a naturally occurring non-neurotropic strain of poliovirus Type 3. It shows a slight immunological difference from Saukett, and also differs from it in temperature stability.

3. The significance of four different isolations of this agent in a brief period is discussed.

Type
Research Article
Information
Journal of Hygiene , Volume 59 , Issue 1 , March 1961 , pp. 57 - 63
Copyright
Copyright © Cambridge University Press 1961

References

REFERENCES

Abel, P. M. (1957). Adenovirus infections. M.Sc. Thesis, University of Otago.Google Scholar
Andrewes, C. H. & Horstmann, D. M. (1949). The susceptibility of viruses to ethyl ether. J. gen. Microbiol. 3, 290.CrossRefGoogle ScholarPubMed
Archetti, I. & Horsfall, F. L. (1950). Persistent antigenic variation of Influenza A viruses after incomplete neutralisation in ovo with heterologous immune sera. J. exp. Med. 92, 441.CrossRefGoogle Scholar
Bodian, D. (1959). Poliomyelitis: pathogenesis and histopathology. In Viral and Rickettsial Infections of Man, 3rd ed. p. 497. Editors Ribers, T. M. and Horsfall, F. L.. Philadelphia: J. B. Lippincott Co.Google Scholar
Dubes, G., Archetti, I. & Wenner, H. A. (1959). Antigenic variations among Type 3 polioviruses. Amer. J. Hyg. 70, 91.Google ScholarPubMed
Hale, J. H., Doraisingham, M., Kanagaratnam, K., Leong, K. W. & Monteiro, E. S. (1959). Large-scale use of Sabin Type 2 attenuated poliovirus vaccine in Singapore during a Type 1 poliomyelitis epidemic. Brit. med. J. 1, 1541.CrossRefGoogle ScholarPubMed
Koprowski, H. (1955). Immunisation of man against poliomyelitis with attenuated preparations of living virus. Ann. N.Y. Acad. Sci. 61, 1039.CrossRefGoogle ScholarPubMed
Melnick, J. L. (1956). Tissue culture methods for the cultivation of poliomyelitis and other viruses. In Diagnostic Procedures for Virus and Rickettsial Diseases, 2nd ed. p. 97. New York: American Public Health Ass.Google Scholar
Melnick, J. L. & Sabin, A. B. (1959). The ECHO virus group. In Viral and Rickettsial Infections of Man, 3rd ed. p. 547. Editors Rivers, T. M. and Horsfall, F. L.. Philadelphia: J. B. Lippincott Co.Google Scholar
Reed, L. J. & Muench, H. (1938) A simple method of estimating fifty per cent endpoints. Amer. J. Hyg. 27, 493.Google Scholar
Sabin, A. B. (1957). Properties and behaviour of orally administered attenuated poliovirus vaccine. J. Amer. Med. Ass. 164, 1216.CrossRefGoogle ScholarPubMed