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Investigation of an outbreak of adenovirus type 3 infection in a boys' boarding school

Published online by Cambridge University Press:  19 October 2009

S. B. Payne ,
E. A. Grilli ,
A. J. Smith  and
T. W. Hoskins
S. B. Payne
Affiliation:
Public Health Laboratory, St Luke's Hospital, Guildford, Surrey GU1 3NT
E. A. Grilli
Affiliation:
Public Health Laboratory, St Luke's Hospital, Guildford, Surrey GU1 3NT
A. J. Smith
Affiliation:
Public Health Laboratory, St Luke's Hospital, Guildford, Surrey GU1 3NT
T. W. Hoskins
Affiliation:
Medical Officer, Christ's Hospital, Horsham, Sussex RH13 7LT
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Summary

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An outbreak of pharyngoconjunctival fever caused by adenovirus type 3 was studied in a boarding school for 800 boys aged 11–18 years. A total of 96 clinical cases were confirmed by laboratory tests. Clinical infection rates were higher in the younger boys but total infection rates did not vary with age. Previous infection provided 88% protection against reinfection.

The techniques of virus isolation, complement fixation and neutralization were compared in the diagnosis of cases. Virus isolation diagnosed 86% of confirmed cases. Where acute sera (collected at onset) and convalescent sera (collected within one month) were available complement fixation and neutralization tests each diagnosed 96% of cases.

Type
Research Article
Information
Journal of Hygiene , Volume 93 , Issue 2 , October 1984 , pp. 277 - 283
Copyright
Copyright © Cambridge University Press 1984

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