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Factors associated with diarrhoea in young children and incidence of symptomatic rotavirus infection in rural West Bengal, India

  • S. PANDA (a1), A. K. DEB (a1), M. CHAWLA-SARKAR (a1), T. RAMAMURTHY (a1), S. GANGULY (a1), P. PRADHAN (a1), A. CHAKRABORTY (a1), S. DESAI (a2), M. D. GUPTE (a2) and R. DHERE (a2)...

Summary

Socio-behavioural factors and pathogens associated with childhood diarrhoea are of global public health concern. Our survey in 696 children aged ⩽2 years in rural West Bengal detected rotavirus as sole pathogen in 8% (17/199) of diarrhoeic stool specimens. Other organisms were detected along with rotavirus in 11% of faecal specimens. A third of the children with rotavirus diarrhoea, according to Vesikari score, had severe illness. The top four rotavirus genotypes were G9P[4] (28%), G1P[8] (19%), G2P[4] (14%) and G8P[4] (8%). In the multivariate model, the practice of ‘drawing drinking water by dipping a pot in the storage vessel’ [adjusted odds ratio (aOR) 2·21, 95% confidence interval (CI) 1·03–4·74, P = 0·041], and ‘children aged ⩽6 months with non-exclusive breastfeeding’ (aOR 2·07, 95% CI 1·1–3·82, P = 0·024) had twice the odds of having diarrhoea. Incidence of rotavirus diarrhoea was 24/100 child-years in children aged >6–18 months, 19/100 child-years in children aged >18–24 months and 5/100 child-years in those aged ⩽6 months. Results have translational implications for future interventions including vaccine development.

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Corresponding author

* Author for correspondence: Dr S. Panda, Division of Epidemiology, National Institute of Cholera & Enteric Diseases (NICED)/Indian Council of Medical Research (ICMR), P-33 C.I.T. Road, Scheme-XM, Beliaghata, Kolkata – 700010, India. (Email: pandasamiran@gmail.com)

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Keywords

Factors associated with diarrhoea in young children and incidence of symptomatic rotavirus infection in rural West Bengal, India

  • S. PANDA (a1), A. K. DEB (a1), M. CHAWLA-SARKAR (a1), T. RAMAMURTHY (a1), S. GANGULY (a1), P. PRADHAN (a1), A. CHAKRABORTY (a1), S. DESAI (a2), M. D. GUPTE (a2) and R. DHERE (a2)...

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