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Direct Conglutination with Rickettsia Burneti, the Causal Agent of Q Fever

Published online by Cambridge University Press:  15 May 2009

H. Barber
H. Barber
Affiliation:
Department of Pathology, University of Cambridge
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Summary

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1. Direct conglutination has been demonstrated with Rickettsia burneti.

2. Sera from human volunteers inoculated with killed suspensions of R. burneti and from persons who had recovered from an attack of Q fever as well as sera from a small number of healthy blood donors were all examined by the direct conglutination reaction, the haemolytic-complement fixation test and the direct agglutination test. A good correlation was found between the titres of the direct conglutination reaction and the haemolytic complement-fixation test but the results with the direct agglutination test were unreliable.

Type
Research Article
Information
Journal of Hygiene , Volume 53 , Issue 1 , March 1955 , pp. 63 - 75
Copyright
Copyright © Cambridge University Press 1955

References

Bengtson, I. A. (1941) Complement fixation in ‘Q’ fever. Proc. Soc. exp. Biol., N.Y., 46, 665.CrossRefGoogle Scholar
Bordet, J. & Streng, O. (1909) Les phénomènes d'adsorption et la conglutinine du sérum de bœeuf. Zbl. Bakt. (1. Abt. Orig.), 49, 260.Google Scholar
Burnet, F. M. & Freeman, M. (1939) Note of a series of laboratory infections with the rickettsia of ‘Q’ fever. Med, J. Aust. i, 11.CrossRefGoogle Scholar
Coombs, A. M. & Coombs, R. R. A. (1953) The conglutination phenomenon. IX. The production of immunoconglutinin in rabbits. J. Hyg., Camb., 51, 509.Google ScholarPubMed
Coombs, R. R. A. & Stoker, M. G. P. (1951) Detection of Q fever antibodies by the antiglobulin sensitisation test. Lancet, ii, 15.CrossRefGoogle Scholar
Hole, N. H. & Coombs, R. R. A. (1947 a). The conglutination phenomenon. I. An introduction to the conglutination phenomenon and an account of the observations and views of previous investigators. J. Hyg., Camb., 45, 480.Google Scholar
Hole, N. H. & Coombs, R. R. A. (1947 b). The conglutination phenomenon. II. The technique of the conglutinating complement absorption test compared with the haemolytic complement fixation test. J. Hyg., Camb., 45, 490.Google Scholar
Lennette, E. H., Clark, W. H., Jensen, F. W. & Toomb, C. J. (1952) Q fever studies. XV. Development and persistence in man of complement-fixing and agglutinating antibodies to Coxiella burnetii. J. Immunol. 68, 591.CrossRefGoogle ScholarPubMed
Lucas, W. P., Fitzgerald, J. G. & Schorer, E. H. (1910) Methods of serum diagnosis in bacillary dysentery (infectious diarrhea) in infants. J. Amer. med. Ass. 54, 441.CrossRefGoogle Scholar
Luoto, L. (1953) A capillary agglutination test for bovine Q fever. J. Immunol. 71, 226.CrossRefGoogle ScholarPubMed
Stoker, M. G. P. (1953) Variation in complement-fixing activity of Rickettsia burneti during egg adaptation. J. Hyg., Camb., 51, 311.CrossRefGoogle ScholarPubMed
Streng, O. (1909) Studien über das verhalten des Rinder-serums gegenüber den Mikroben. Zbl. Bakt. (1. Abt. Orig.), 50, 47.Google Scholar