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Community-wide outbreak of Escherichia coli O157:H7 associated with consumption of frozen beef burgers

  • L. A. KING (a1) (a2), A. MAILLES (a1), P. MARIANI-KURKDJIAN (a3), C. VERNOZY-ROZAND (a4), M. P. MONTET (a4), F. GRIMONT (a5), N. PIHIER (a6), H. DEVALK (a1), F. PERRET (a7), E. BINGEN (a3), E. ESPIÉ (a1) and V. VAILLANT (a1)...

Summary

On 24–25 October 2005 a cluster of five haemolytic uraemic syndrome (HUS) cases was reported in southwest France. An investigation was undertaken to identify the outbreak source and implement control measures. Cases were defined as individuals with HUS or diarrhoea with isolation of Escherichia coli O157:H7 in stools or a positive antibody response to E. coli O157 lipopolysaccharide, resident in southwest France with symptom onset after 19 September 2005. Sixty-nine identified patients had symptom onset between 5 October and 3 November 2005, including 17 cases of HUS. One brand of frozen beef burgers produced on 22 August 2005 was consumed by all patients in the week before symptom onset. E. coli O157:H7 strains from patients, patients' burgers and the manufacturing plant were genetically related. This is the largest community-wide outbreak of E. coli O157:H7 in France to date and the first associated with consumption of contaminated frozen beef burgers.

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Copyright

Corresponding author

*Author for correspondence: L. A. King, Département Maladies Infectieuses, Institut de Veille Sanitaire, 12 rue du Val d'Osne, 94415 Saint-Maurice Cedex, France. (Email: l.king@invs.sante.fr)

References

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1. Braam, P. Diarrhea caused by enterohemorrhagic strains. In: Heymann, DLed. Control of Communicable Diseases Manual, 18th edn. Washington, DC: American Public Health Association, 2004, pp. 160171.
2. Thorpe, CM. Shiga toxin-producing Escherichia coli infection. Clinical Infectious Diseases 2004; 38: 12981303.
3. Tarr, PI, Gordon, CA, Chandler, WL. Shiga-toxin-producing Escherichia coli and hemolytic uraemic syndrome. Lancet 2005; 365: 10731086.
4. Decludt, B, et al. Haemolytic uraemic syndrome and Shiga toxin-producing Escherichia coli infection in children in France. Epidemiology and Infection 2000; 124: 215220.
5. Espié, E, et al. Surveillance of hemolytic uremic syndrome in children aged less than 15 years in France, 2002 and 2003 [in French]. Bulletin Epidémiologique Hebdomadaire 2004; 42: 203204 (http://www.invs.sante.fr/beh/2004/42/beh_42_2004.pdf). Accessed 28 July 2008.
6. Bidet, P, et al. Characterization of Escherichia coli O157:H7 isolates causing haemolytic uraemic syndrome in France. Journal of Medical Microbiology 2005; 54: 7175.
7. Vernozy-Rozand, C, et al. Prevalence of Escherichia coli O157:H7 in industrial minced beef. Letters in Applied Microbiology 2002; 35: 711.
8. Tenover, FC, et al. Interpreting chromosomal DNA restriction patterns produced by pulsed-field gel electrophoresis: criteria for bacterial strain typing. Journal of Clinical Microbiology 1995; 33: 22332239.
9. Espié, E, et al. Escherichia coli O157 outbreak associated with fresh unpasteurized goats' cheese. Epidemiology and Infection 2006; 134: 143146.
10. Haeghebaert, S, et al. Surveillance of hemolytic uremic syndrome in children aged less than 15 years in France in 2001 [in French]. Bulletin Epidémiologique Hebdomadaire 2003; 20: 8991 (http://www.invs.sante.fr/beh/2003/20/beh_20_2003.pdf). Accessed 28 July 2008.
11. Espié, E, et al. Risk factors for sporadic cases of hemolytic uremic syndrome in children aged less than 15 years in France: case control study 2000–2001 [in French]. Bulletin Epidémiologique Hebdomadaire 2003; 20: 9192 (http://www.invs.sante.fr/beh/2003/20/beh_20_2003.pdf). Accessed 28 July 2008.
12. Rangel, JM, et al. Epidemiology of Escherichia coli O157:H7 outbreaks, United States, 1982–2002. Emerging Infectious Diseases 2005; 11: 603609.
13. Tuttle, J, et al. Lessons from a large outbreak of Escherichia coli O157:H7 infections: insights into the infectious dose and method of widespread contamination of hamburger patties. Epidemiology and Infection 1999; 122: 185192.
14. Vogt, RL, Dippold, L. Escherichia coli O157:H7 outbreak associated with consumption of ground beef, June–July 2002. Public Health Reports 2005; 120: 174178.
15. Centers for Disease Control and Prevention. Escherichia coli O157:H7 infections associated with eating a nationally distributed commercial brand of frozen ground beef patties and burgers – Colorado, 1997. Morbidity and Mortality Weekly Report 1997; 46: 777778.
16. Belongia, EA, et al. An outbreak of Escherichia coli O157:H7 colitis associated with consumption of precooked meat patties. Journal of Infectious Diseases 1991; 164: 338343.
17. Haeghebaert, S, et al. Minced beef and human salmonellosis: review of the investigation of three outbreaks in France. Eurosurveillance 2001; 6(2): 2126.
18. Chapman, PA, et al. Cattle as a possible source of verotoxin-producing Escherichia coli O157 infection in man. Epidemiology and Infection 1993; 111: 439447.
19. Elder, RO, et al. Correlation of enterohemorrhagic Escherichia coli O157 prevalence in feces, hides, and carcasses of beef cattle during processing. Proceedings of the National Academy of Sciences USA 2000; 97: 29993003.
20. Maki, DG. Don't eat the spinach – controlling foodborne infectious disease. New England Journal of Medicine 2006; 355: 19521955.
21. Griffin, PM, Tauxe, RV. The epidemiology of infections caused by Escherichia coli O157:H7, other enterohemorragic E. coli and the associated haemolytic uremic syndrome. Epidemiologic Reviews 1991; 13: 6098.
22. Tarr, PI. Escherichia coli O157:H7: clinical, diagnostic, and epidemiological aspects of human infection. Clinical Infectious Diseases 1995; 20: 110.
23. Ochoa, TJ, Cleary, TG. Epidemiology and spectrum of disease of Escherichia coli O157; Current Opinion in Infectious Diseases 2003; 102: 259263.
24. Bielaszewska, M, et al. Shiga toxin activatable by intestinal mucus in Escherichia coli isolated from humans: predictor for a severe clinical outcome. Clinical Infectious Diseases. 2006; 43: 11601167.
25. Werber, D, et al. Looking for tips to find icebergs – surveillance of haemolytic uraemic syndrome to detect outbreaks of shiga-toxin producing E. coli infection. Eurosurveillance 2008; 13(9) (http://www.eurosurveillance.org/images/dynamic/EE/V13N09/art8053.pdf). Accessed 3 October 2008.
26. Institut de Veille Sanitaire. Evaluation of the surveillance of typical or post-diarrhoeal haemolytic uremic syndrome in France, 19962003 [in French] (http://www.invs.sante.fr/publications/2006/shu_1996_2003/shu_1996_2003.pdf). Accessed 29 July 2008.

Keywords

Community-wide outbreak of Escherichia coli O157:H7 associated with consumption of frozen beef burgers

  • L. A. KING (a1) (a2), A. MAILLES (a1), P. MARIANI-KURKDJIAN (a3), C. VERNOZY-ROZAND (a4), M. P. MONTET (a4), F. GRIMONT (a5), N. PIHIER (a6), H. DEVALK (a1), F. PERRET (a7), E. BINGEN (a3), E. ESPIÉ (a1) and V. VAILLANT (a1)...

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