Skip to main content Accessibility help
×
×
Home

Chronic atrophic oral candidiasis among patients with diabetes mellitus – role of secretor status

  • F. Z. Aly (a1), C. C. Blackwell (a1), D. A. C. MacKenzie (a1), D. M. Weir (a1), R. A. Elton (a2), C. G. Cumming (a3), J. A. Sofaer (a3) and B. F. Clarke (a4)...

Summary

Non-diabetic individuals who are non-secretors of blood group antigens are prone to superficial infections by Candida albicans. In this study, 216 patients with diabetes mellitus who were denture wearers were examined for the presence or absence of denture stomatitis. There was an overall trend for non-secretors to be prone to denture stomatitis compared with secretors. Stepwise linear discriminant analysis was used to dissect the contribution of secretor status and other variables to the development of the disease. Secretor status was found to be a contributory factor among patients with non-insulin dependent diabetes but not among those with insulin-dependent diabetes. The possible reasons for this are discussed.

    • Send article to Kindle

      To send this article to your Kindle, first ensure no-reply@cambridge.org is added to your Approved Personal Document E-mail List under your Personal Document Settings on the Manage Your Content and Devices page of your Amazon account. Then enter the ‘name’ part of your Kindle email address below. Find out more about sending to your Kindle. Find out more about sending to your Kindle.

      Note you can select to send to either the @free.kindle.com or @kindle.com variations. ‘@free.kindle.com’ emails are free but can only be sent to your device when it is connected to wi-fi. ‘@kindle.com’ emails can be delivered even when you are not connected to wi-fi, but note that service fees apply.

      Find out more about the Kindle Personal Document Service.

      Chronic atrophic oral candidiasis among patients with diabetes mellitus – role of secretor status
      Available formats
      ×

      Send article to Dropbox

      To send this article to your Dropbox account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Dropbox.

      Chronic atrophic oral candidiasis among patients with diabetes mellitus – role of secretor status
      Available formats
      ×

      Send article to Google Drive

      To send this article to your Google Drive account, please select one or more formats and confirm that you agree to abide by our usage policies. If this is the first time you use this feature, you will be asked to authorise Cambridge Core to connect with your <service> account. Find out more about sending content to Google Drive.

      Chronic atrophic oral candidiasis among patients with diabetes mellitus – role of secretor status
      Available formats
      ×

Copyright

References

Hide All
1.Budtz-Jorgensen, E. The significance of C. albicans in denture stomatitis. Scand J Dent Res 1974; 82: 151–90.
2.Cawson, RA. Denture sore mouth and angular cheilitis. Oral candidiasis in adults. Br Dental J 1963; 155: 441–9.
3.Odds, FC. Factors that predispose the host to candidiasis. In: Candida and candidasis: A review and bibliography. 2nd ed.Baillière Tindall, 1988: 93114.
4.Blackwell, CC. Genetic susceptibility to infectious agents. Proc Roy Coll Phys Edin 1989; 19: 129–35.
5.Thom, SM, Blackwell, CC, MacCallum, C et al. , Non-secretion of ABO blood group antigens and susceptibility to infection by Candida species. FEMS Microbiol Immunol 1989; 47: 401–6.
6.Burford-Mason, AP, Welsby, JCP, Willoughby, JMT. Oral carriage of Candida albicans, ABO blood group and secretor status in healthy individuals. J Med Veter Mycol 1988; 26: 4956.
7.Blackwell, CC, Aly, FZM, James, VS et al. , Blood group, secretor status and oral carriage of yeasts among patients with diabetes mellitus. Diabetic Res 1989; 12: 101–4.
8.Mollison, PL. Blood transfusion in clinical medicine, 6th ed.Oxford: Blackwell, 1979; 414–82.
9.Milne, LJR. Fungi. In: Practical medical microbiology. 13th ed.Edinburgh: Churchill Livingstone, 1988: 675–99.
10.Halperin, V, Kolab, S, Jefferis, KR, Huddleston, SO, Robinson, HBG. The occurrence of Fordyce spots, benign migratory glossitis, median rhomboid glossitis and fissured tongue in 2478 dental patients. Oral Surg Oral Med Oral Pathol 1953; 6: 1072–7.
11.McCarthy, FP. A clinical and pathologic study of oral disease. JAMA 1941; 16: 116.
12.Farman, AG. Atrophic lesions of the tongue: a prevalence study among 175 diabetic patients. J Oral Pathol 1976; 5: 255–64.
13.Sharon, A, Ben-Ayreh, H, Etzhak, B, Yoram, K, Szargel, R, Gulman, D. Salivary composition in diabetic patients. J Oral Med 1985; 40: 23–6.
14.Davenport, JC. The oral distribution of Candida in denture stomatitis. Br Dent J 1970; 129: 151–6.
15.Cawson, RA. Chronic oral candidiasis, denture stomatitis and chronic hyperplastic candidiasis. In: Winner, HI, Hurley, eds. Symposium on candidal infections. Edinburgh: Churchill Livingstone, 1964; 138–53.
16.Budtz-Jörgensen, E. An epidemiological study of yeasts in elderly denture wearers. Community Dent Oral Epidemiol 1975; 3: 115–9.
17.Budtz-Jörgensen, E, Bertram, V. Denture stomatitis. I. The etiology in relation to trauma and infection. Acta Odontol Scand 1970; 28: 7192.
18.Neil, DJ. Symposium on denture sore mouth I. An etiology review. Dent Practit 1965; 16: 135–8.
19.Nyquist, G. Denture sore mouth. Acta Odont Scand 1952; 10: Suppl. 9.
20.Arendorf, TM, Walker, DM, Kingdom, RJ, Roll, JRS, Newcombe, RG. Tobacco smoking and denture wearing in oral candidal leukoplakia. Br Dent J 1983; 155: 340–3.
21.Vogt, FC. The incidence of oral candidiasis with use of inhaled corticosteroid. Ann Allergy 1979; 43: 205–10.
22.Lamey, PJ. Secretor status, candidal carriage and candidal infection in patients with diabetes mellitus. J Oral Pathol 1988; 17: 354–7.
23.Turrell, AJW. Aetiology of inflamed upper denture-bearing tissues. Br Dent J 1966; 120: 542–6.
Recommend this journal

Email your librarian or administrator to recommend adding this journal to your organisation's collection.

Epidemiology & Infection
  • ISSN: 0950-2688
  • EISSN: 1469-4409
  • URL: /core/journals/epidemiology-and-infection
Please enter your name
Please enter a valid email address
Who would you like to send this to? *
×

Metrics

Full text views

Total number of HTML views: 0
Total number of PDF views: 0 *
Loading metrics...

Abstract views

Total abstract views: 0 *
Loading metrics...

* Views captured on Cambridge Core between <date>. This data will be updated every 24 hours.

Usage data cannot currently be displayed