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Brucellosis in Northern Ireland. A serological survey

Published online by Cambridge University Press:  15 May 2009

D. G. McDevitt
Affiliation:
Department of Therapeutics and Pharmacology, The Queen's University of Belfast
W. J. McCaughey
Affiliation:
The Veterinary Research Laboratories, Stormont, Belfast
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Summary

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A serological survey for brucella antibodies has been carried out in Northern Ireland in an attempt to assess the effects of the brucellosis eradication programme in cattle which has been in progress since 1959. One thousand eight hundred and ninety four sera from blood donors, from farmer's lung tests, and from various groups occupationally exposed to cattle were examined by the serum agglutination test, the anti-human globulin (A.H.G.) (Coombs) test and the complement-fixation test.

The incidence of brucellosis in Northern Ireland is now less than it was 20 years ago, but is similar to that reported in a recent survey in England. It now appears that the principal method of transmission of brucellosis in the province is by occupational exposure rather than by drinking infected milk. Though it may be too early to make a serological assessment of the effects on human infections of brucellosis eradication in cattle, this survey provides a basis for future evaluation.

We thank Prof. O. L. Wade, Prof. P. C. Elmes and Dr W. R. Kerr for their encouragement and helpful advice; the Medical Officers of Health in Antrim, Armagh, Down and Fermanagh, Londonderry, and Tyrone, and in Belfast and Londonderry County Borough for help in obtaining blood samples; Dr M. C. Huth of the Northern Ireland Blood Transfusion Service, for sera; Dr D. W. R. Mackenzie and Miss H. E. Cairns for sera from the Mycology Diagnostic Laboratory; Dr J. H. Connolly for sera from the Virus Reference Laboratory, and for helpful advice; the farm workers and veterinary surgeons for volunteering blood samples; the technical staff of the Veterinary Research Laboratories for carrying out the tests.

Type
Research Article
Copyright
Copyright © Cambridge University Press 1969

References

Alton, G. G. & Jones, L. M. (1967). Laboratory techniques in brucellosis. Monograph Ser. W.H.O. No. 55.Google ScholarPubMed
Anon. (1966). Brucellosis fiasco. Br. med J. ii, 63.Google Scholar
Barrett, G. M. & Rickards, A. G. (1953). Chronic Brucellosis. Q. Jl Med. 22, 23.Google ScholarPubMed
Bartram, G. H., Bothwell, P. W., Jebb, W. H. H.McDiarmid, A. & Preston, A. E. (1963). Brucella abortus agglutinins in the sera of pregnant women and blood donors. Br. J. prev. soc. Med. 17, 95.Google ScholarPubMed
Bothwell, P. W. (1960). Symposium on brucellosis. (4) Epidemiology and prevention of human brucellosis. Vet. Rec. 72, 933.Google Scholar
Bothwell, P. W. (1963). Epidemiology of human brucellosis in the United Kingdom. Br. J. prev. soc. Med. 17, 90.Google ScholarPubMed
Bothwell, P. W., McDiarmid, A., Bartram, H. G., Mackenzie-Wintle, H. A. & Williamson, A. R. H. (1963). Brucellosis control and eradication. Publ. Hlth, Lond, 77, 135.CrossRefGoogle ScholarPubMed
Bradstreet, C. P. M. & Taylor, C. E. D. (1962). Technique of complement fixation test applicable to the diagnosis of virus diseases. Mon. Bull. Minist. Hlth 21, 96.Google Scholar
Brodigan, M., McDiarmid, A., Mann, P. G. & Skone, J. E. (1961). Brucellosis—an island epidemiological study. Br. med. J. ii, 1393.CrossRefGoogle Scholar
Brucellosis Control Order (1962). S. R. and O. (N.I.) No. 222.Google Scholar
Brucellosis Order (1960). S. R. and O. (N.I.) No. 110.Google Scholar
Christie, T. E., Kerr, W. R. & McCaughey, W. J. (1968). Brucellosis eradication in Northern Ireland. Vet. Rec. 82, 176.Google Scholar
Coetzee, J. N. (1956). Human brucella anti-globulin titres in the Pretoria area. S. Afr. J. Lab. clin. Med. 2, 259.Google Scholar
Dalrymple-Champneys, W. W. (1929). Undulant fever, with special reference to animal sources of infection and the possibility of its prevalence in England and Wales. Rep. publ. Hlth med. Subj., Lond. No. 56.Google Scholar
Dalrymple-Champneys, W. W. (1960). Brucella infection and undulant fever in man. London: Oxford University Press.Google Scholar
Ferris, A. A., Stevenson, W. J. & Lewis, F. A. (1953). The anti-globulin sensitisation test as applied to brucella infection: A preliminary report. Med. J. Aust. i, 619.CrossRefGoogle Scholar
Huddleson, I. F. & Johnson, H. W. (1930). Brucellosis. I. The significance of brucella agglutinins in the blood of veterinarians. J. Am. med. Ass., 94, 1905.CrossRefGoogle Scholar
Kerr, W. R. & Rankin, J. F. (1963). The eradication of brucellosis in Northern Ireland. J. Soc. Dairy Technol. 16, 214.CrossRefGoogle Scholar
Kerr, W. R., Coghlan, J. D., Payne, D. J. H. & Robertson, L. (1966 a). Chronic brucellosis in the practising veterinary surgeon. Vet. Rec. 79, 602.Google Scholar
Kerr, W. R., Coghlan, J. D., Payne, D. J. H. & Robertson, L. (1966 b). The laboratory diagnosis of chronic brucellosis. Lancet ii, 1181.CrossRefGoogle Scholar
McDevitt, D. G. (1968). Studies in human brucellosis. M. D. Thesis, The Queen's University, Belfast.Google Scholar
Milk Act (Northern Ireland) (1950). c. 31.Google Scholar
Milk (Amendment No. 2) Regulations (1959). S. R. and O. (N.I.) No. 68.Google Scholar
Murdock, C. R. (1944). Studies on the Brucella abortus. M.D. Thesis, The Queen's University, Belfast.Google Scholar
Parry, W. H. (1966). Milk-borne diseases: An epidemiological review. Lancet ii, 216.CrossRefGoogle Scholar
Schrire, L. (1962). Human brucellosis in South Africa. S. Afr. med. J. 36, 342.Google ScholarPubMed
Spink, W. W. (1956). The Nature of Brucellosis. Minneapolis: University of Minnesota Press.Google Scholar
Wilson, M. M. & Merrifield, E. V. O. (1951). The anti-globulin (Coombs) test in brucellosis. Lancet ii, 913.CrossRefGoogle Scholar
Zoutendyk, A. (1958). Incomplete antibodies in brucellosis: An indirect anti-globulin (Coombs) one-tube screen test. S. Afr. med. J. 32, 706.Google Scholar