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An epidemic of rotavirus diarrhoea in Jawhar Taluk, Thane district, Maharashtra, India, December 2000–January 2001

Published online by Cambridge University Press:  26 February 2004

S. D. KELKAR
Affiliation:
Rotavirus Department, National Institute of Virology, 20-A, Dr Ambedkar Road, Pune – 411 001, India
P. G. RAY
Affiliation:
Rotavirus Department, National Institute of Virology, 20-A, Dr Ambedkar Road, Pune – 411 001, India
N. SHINDE
Affiliation:
Patang Shah Cottage Hospital, Jawhar, Thane District, Maharashtra, India
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Abstract

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An epidemic of diarrhoea in Jawhar, a tribal area of Thane district, Maharashtra, India was investigated. Within a period of approximately 2 months 490 cases of acute diarrhoea were reported among children under 5 years of age, with a case fatality rate of 0·40%. Twenty-seven out of 39 (69·23%) rectal swabs/faecal specimens obtained from hospitalized paediatric patients up to 2 years of age from Jawhar were positive by ELISA for rotavirus. Of these, seven were in the age group of [les ]6 months. Seven ELISA-positive faecal specimens were positive for serotype G3 by RT–PCR. Out of 15 serum samples collected from these patients, 12 showed the presence of rotavirus-specific IgM. Rotavirus appears to be the aetiological agent of this widespread outbreak in Jawhar, Thane district, Maharashtra state, India.

Type
Research Article
Copyright
© 2004 Cambridge University Press