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Cross-Country Discrepancies in Monkeypox Vaccine Hesitancy Among Postgraduate and Undergraduate Medical Students

Published online by Cambridge University Press:  02 May 2024

Mai Hussein Open the ORCID record for Mai Hussein [Opens in a new window] ,
Abdelmonem Siddiq ,
Horeya M. Ismail ,
Norhan Mansy ,
Doha El-Sayed Ellakwa ,
Mohammed Nassif ,
Areej A. Hussein ,
Jubran K. Abdullah Alzedaar ,
Chukwuagoziem A. Iloanusi  and
Murad O. Omran
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Mai Hussein*
Affiliation:
Alexandria Clinical Research Administration, Alexandria Health Affairs Directorate, Egypt Ministry of Health and Population, Egypt
Abdelmonem Siddiq
Affiliation:
Faculty of Pharmacy, Mansoura University, Mansoura, Egypt
Horeya M. Ismail
Affiliation:
High Institute of Public Health, Alexandria University, Egypt
Norhan Mansy
Affiliation:
Clinical pharmacy department, New Cairo Hospital, Egypt
Doha El-Sayed Ellakwa
Affiliation:
Biochemistry Department, Faculty of Pharmacy, Al-Azhar University, Egypt Department of Biochemistry, Faculty of Pharmacy, Sinai University, Kantara Branch, Ismailia, Egypt
Mohammed Nassif
Affiliation:
Faculty of Medicine, Alexandria University, Egypt
Areej A. Hussein
Affiliation:
Microbiology Department, College of Medicine, University of Diyala, Iraq
Jubran K. Abdullah Alzedaar
Affiliation:
College of Medicine, University of Medical and Applied Sciences, Sanaa, Yemen
Chukwuagoziem A. Iloanusi
Affiliation:
Faculty of Clinical Sciences, University of Uyo, Uyo, Nigeria
Murad O. Omran
Affiliation:
Department of Physiology, Faculty of Medicine, Universiti of Malaya, Kuala Lumpur, Malaysia
Khalil M. Rourou
Affiliation:
University of Medicine and Pharmacy of Iași, Romania
Tarun K. Suvvari
Affiliation:
Rangaraya Medical College, Kakinada, India
Saja Yazbek
Affiliation:
Faculty of Public Health, Lebanese University, Beirut, Lebanon
Ramy M. Ghazy
Affiliation:
Family and Community Medicine Department, Family and Community Medicine Department, College of Medicine, King Khalid University, Abha, Saudi Arabia Tropical Health Department, High Institute of Tropical Health, Alexandria University, Alexandria, Egypt
*
Corresponding author: Mai Hussein; Email: Mai.mk.hussein@gmail.com.
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Abstract

Background:

Medical students hold significant importance, as they represent the future of healthcare provision. This study aimed to explore psychological antecedents towards the monkeypox (mpox) vaccines among postgraduate and undergraduate medical students across countries.

Methods:

A cross-sectional survey was conducted among medical students aged 18 years old and above in 7 countries; Egypt, Romania, Malaysia, and Yemen, Iraq, India, and Nigeria. We used social media platforms between September 27 and November 4, 2022. An anonymous online survey using the 5C scale was conducted using snowball and convenience Sampling methods to assess the 5 psychological antecedents of vaccination (i.e., confidence, constraints, complacency, and calculation, as well as collective responsibility).

Results:

A total of 2780 participants were recruited. Participants’ median age was 22 years and 52.1% of them were males. The 5C psychological antecedents of vaccination were as follows: 55% were confident about vaccination, 10% were complacent, 12% experienced constraints, and 41% calculated the risk and benefit. Lastly, 32% were willing to be vaccinated for the prevention of infection transmission to others. The Country was a significant predictor of confidence, complacency, having constraints, and calculation domains (P < 0.001). Having any idea about the mpox vaccine was linked to 1.6 times higher odds of being more confident [OR = 1.58 (95% CI, 1.26–1.98), P < 0.001] Additionally, living in a rural area significantly increased complacency [OR = 1.42 (95% CI, 1.05–1.95), P = 0.024] as well as having anyone die from mpox [OR = 3.3 (95% CI, 1.64–6.68), P < 0.001]. Education level was associated with increased calculation [OR = 2.74 (95% CI, 1.62–4.64), P < 0.001]. Moreover, being single and having no chronic diseases significantly increased the calculation domain [OR = 1.40 (95% CI, 1.06–1.98), P = 0.02] and [OR = 1.54 (95% CI, 1.10–2.16), P = 0.012] respectively. Predictors of collective responsibility were age 31–45 years [OR = 2.89 (95% CI, 1.29–6.48), P = 0.01], being single [OR = 2.76 (95% CI, 1.94 -3.92), P < 0.001], being a graduate [OR = 1.59 (95% CI (1.32–1.92), P < 0.001], having no chronic disease [OR = 2.14 (95% CI, 1.56–2.93), P < 0.001], and not knowing anyone who died from mpox [OR = 2.54 (95% CI, 1.39–4.64), P < 0.001), as well as living in a middle-income country [OR = 0.623, (95% CI, 0.51–0.73), P < 0.001].

Conclusions:

This study underscores the multifaceted nature of psychological antecedents of vaccination, emphasizing the impact of socio-demographic factors, geographic location, and awareness, as well as previous experiences on individual attitudes and collective responsibility towards vaccination.

Keywords

monkeypoxvaccinehesitancymedical students5C questionnaire
Type
Original Research
Information
Disaster Medicine and Public Health Preparedness , Volume 18 , 2024 , e82
Copyright
© The Author(s), 2024. Published by Cambridge University Press on behalf of Society for Disaster Medicine and Public Health, Inc

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